| 引用本文:骆赟韵1，2，李佳阳1，黎小斌1，2.基于关联规则的当代中医妇科名家痛经用药规律数据挖掘〖JZ)〗〖HS)〗[J].世界中医药,2019,(05):. |
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| 基于关联规则的当代中医妇科名家痛经用药规律数据挖掘〖JZ)〗〖HS)〗 |
| Data Mining of Regulation of Prescriptions of Contemporary Masters of TCM Gynecology for Dysmenorrhea Based on Apriori Method |
| 投稿时间：2018-04-24 |
| DOI：10.3969/j.issn.1673-7202.2019.05.026 |
| 中文关键词: 痛经 验案 药物 中医妇科名家 处方 关联规则 Apriori算法；数据 |
| English Keywords:Dysmenorrhea Cases Traditional Chinese medicine Contemporary masters of TCM gynecology Prescription Composition principles of prescriptions Aprior Data |
| 基金项目:广东省科技厅科技计划项目（粤科函规财字［2014］807） |
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| 中文摘要: |
| 目的：拟对当代中医妇科名家治疗痛经的验案进行数据挖掘，找出药物间的关联规则，挖掘核心组合及新处方，分析当代中医妇科名家治疗痛经的用药经验。方法：选取weka软件中关联规则Apriori算法（最小支持度＞0.15，最小置信度＞0.6)对所收集的当代中医妇科名家治疗痛经的验案进行数据挖掘。结果：本研究共选出15位名家302诊痛经医案216味中药进行数据挖掘。出现频数前5位的中药为赤芍、川芎、香附、白芍及当归；置信度前5位的二联药物分别是当归-肉桂、当归-香附、当归-吴茱萸、当归-熟地黄及当归-川芎；置信度前5位的三联药物是当归-川芎-赤芍、当归-川芎-延胡索、当归-川芎-甘草、当归-川芎-白芍及当归-川芎-香附。置信度前5位的四联药物是当归-川芎-白芍-甘草、当归-川芎-香附-白芍及当归-川芎-香附-延胡索。结论：痛经最主要的病机是气血瘀阻，不通则痛；其最重要的治法是行气活血，化瘀止痛。 |
| English Summary: |
| To conduct data mining on prescriptions for dysmenorrhea, find out the association rules between drugs and core prescriptions, and study the experience of contemporary masters of TCM (traditional Chinese medicine) gynecology. Methods:The prescriptions of contemporary masters of TCM gynecology for dysmenorrhea were collected, sorted and entered into weka System to analyze the composition principles through the methods of apriori in weka (support>15％，confidence>0.6)． Results:The study collected 305 prescriptions and 216 medications from 15 doctors to conduct data mining. The study showed that the most frequently used medications were Radix Paeoniae Rubra, Radix Paeoniae Alba, Rhizoma Cyperi, Rhizoma Chuanxiong, and Radix Angelicae Sinensis. The most frequency two-drug-combinations are Radix Angelicae Sinensis-Cortex Cinnamomi, Radix Angelicae Sinensis-Rhizoma Cyperi, Radix Angelicae Sinensis-Fructus Evodiae, Radix AngelicaeSinensis-Rehmannia glutinosa (Gaert.) and Radix Angelicae Sinensis-Rhizoma Chuanxiong. The most frequently used trigeminy medications are Radix Angelicae Sinensis-Rhizoma Chuanxiong-Radix Paeoniae Rubra, Radix Angelicae Sinensis-Rhizoma Chuanxiong-Rhizoma Corydalis, Radix Angelicae Sinensis-Rhizoma Chuanxiong-Radix Glycyrrhizae, Radix Angelicae Sinensis-Rhizoma Chuanxiong-Radix Paeoniae, Alba and Radix Angelicae Sinensis-Rhizoma Chuanxiong-Rhizoma Cyperi. The most frequency tetrageminy medications are Radix Angelicae Sinensis-Rhizoma Chuanxiong-Radix Paeoniae Alba-Radix Glycyrrhizae, Radix Angelicae Sinensis-Rhizoma Chuanxiong-Rhizoma Cyper-Radix Paeoniae Alba and Radix Angelicae Sinensis-Rhizoma Chuanxiong-Rhizoma Cyperi-Rhizoma Corydalis. Conclusion:The most important TCM pathogenesis of dysmenorrhoea is qi stagnation and blood stasis, of which the most important principle of treatment is activating blood circulation to dissipate blood stasis. |
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