| 引用本文:马利阁，尹万乐，尤笑迎.续骨活血法联合手法复位外固定治疗上肢闭合性骨折的疗效及对患者血清炎性反应递质水平的影响〖JZ)〗〖HS)〗[J].世界中医药,2019,(05):. |
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| 续骨活血法联合手法复位外固定治疗上肢闭合性骨折的疗效及对患者血清炎性反应递质水平的影响〖JZ)〗〖HS)〗 |
| Effects of the Bone-setting and Blood-invigorating Method Combined with Manipulative Reduction and External Fixation in the Treatment of Closed Fracture of Upper Limb and on Serum Level of Inflammatory Factors |
| 投稿时间：2018-06-06 |
| DOI：10.3969/j.issn.1673-7202.2019.05.049 |
| 中文关键词: 续骨活血法 手法复位外固定 上肢闭合性骨折 疗效 炎性反应递质 |
| English Keywords:Bone-setting and blood-invigorating method Manipulative reduction and external fixation Closed fracture of upper limb Curative effect Inflammatory factor |
| 基金项目:河南省中医药科学研究专项项目（2017ZY1007） |
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| 中文摘要: |
| 目的：探讨续骨活血法联合手法复位外固定治疗上肢闭合性骨折的疗效及对患者血清炎性反应递质水平的影响。方法：选取2015年6月至2017年6月郑州人民医院收治的上肢闭合性骨折患者106例作为研究对象，按照随机数字表法随机分为对照组和观察组，每组53例。对照组采用手法复位外固定，观察组在对照组基础上结合续骨活血法治疗。2组患者疗程均为12周。比较2组治疗疗效、骨折愈合时间，治疗前后细胞间黏附因子-1（sICAM-1）、疼痛视觉模拟评分法（VAS）和肿胀程度评分、X线评分及血清炎性反应递质白细胞介素-6（IL-6）、肿瘤坏死因子-α（TNF-α）。结果：观察组总有效率（96.23%）高于对照组（81.13%），且差异有统计学意义（P<0.05）。观察组骨折愈合时间快于对照组，差异有统计学意义（P<0.05）。2组治疗后VAS评分和肿胀程度评分降低，差异有统计学意义（P<0.05）；观察组治疗后VAS评分和肿胀程度评分低于对照组，差异有统计学意义（P<0.05）。2组治疗后X线评分增加，差异有统计学意义（P<0.05）；观察组治疗后X线评分高于对照组，差异有统计学意义（P<0.05）。对照组治疗后血清sICAM-1、IL-6和TNF-α水平差异无统计学意义（P>0.05）；观察组治疗后血清sICAM-1、IL-6和TNF-α水平降低，差异有统计学意义（P<0.05）；观察组治疗后血清sICAM-1、IL-6和TNF-α水平低于对照组，差异有统计学意义（P<0.05）。结论：续骨活血法联合手法复位外固定治疗上肢闭合性骨折的疗效显著，且可减轻患者炎性反应。 |
| English Summary: |
| To explore the effects of the bone-setting and blood-invigorating method combined with manipulative reduction and external fixation in the treatment of closed fracture of upper limb，and on patients' serum level of inflammatory factors.Methods:From June 2015 to June 2017，a total of 106 patients with upper limb closed fracture treated in People's Hospital of Zhengzhou were selected as study object，and divided into the observation group(53 cases）and the control group(53 cases）according to random number table method.The control group was treated with manipulative reduction and external fixation，and the observation group was treated with the bone-setting and blood-invigorating method in addition to the procedure of the control group.The treatment course of both groups was 12 weeks.The curative effect of the 2 groups，the time of fracture healing，VAS score，the swelling degree score，the X ray score and the level of serum inflammatory factors were compared before and after the treatment.Results:The total effective rate of the observation group(96.23%）was higher than that of the control group(81.13%)(P<0.05).The time of fracture healing of the observation group was faster than that of the control group(P<0.05).After treatment，the score of VAS and the degree of swelling of the 2 groups decreased(P<0.05)，and the score of VAS and the degree of swelling in the observation group were lower than that of the control group(P<0.05).The X-ray score of the 2 groups increased(P<0.05)，and the X-ray score of the observation group was higher than that of the control group(P<0.05).There was no significant change in serum sICAM-1，IL-6 and TNF-α levels of the control group after the treatment(P>0.05).The levels of serum sICAM-1，IL-6 and TNF-α of the observation group decreased(P<0.05)，and the levels of serum sICAM-1，IL-6 and TNF-α of the observation group were lower than those of the control group(P<0.05).Conclusion:The bone-setting and blood-invigorating method combined with manipulative reduction and external fixation is effective in the treatment of closed fractures of upper limb，and it can reduce the inflammatory reaction of patients，which is of important clinical value. |
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