| 引用本文:吴跃文1，林启有2，戴伟春2.麻杏石甘汤中麻黄与石膏不同剂量配比对治疗肺热喘咳证的临床效果分析[J].世界中医药,2019,(06):. |
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| 麻杏石甘汤中麻黄与石膏不同剂量配比对治疗肺热喘咳证的临床效果分析 |
| Clinical Effect Analysis of Different Dosage Ratio of Herba Ephedrae and Gypsum Fibrosum in Maxing Shigan Decoction for Treating Lung Heat with Panting and Cough Syndrome |
| 投稿时间：2019-02-26 |
| DOI：10.3969/j.issn.1673-7202.2019.06.037 |
| 中文关键词: 麻杏石甘汤 麻黄 石膏 配比 肺热喘咳证 效果 |
| English Keywords:Maxing Shigan Decoction Herba Ephedra Gypsum Fibrosum Ratio Lung heat with panting and cough syndrome Effect |
| 基金项目:佛山市医学类科技攻关项目（2017AB000342）——温阳补肾法合并艾灸及西药治疗虚寒型痛风性关节炎的临床研究 |
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| 中文摘要: |
| 目的：探讨麻杏石甘汤中麻黄与石膏不同剂量配比对治疗肺热喘咳证的临床效果。方法：选取2015年6月至2018年6月广东省人民医院南海医院收治的具有肺热喘咳证的肺炎患者120例作为研究对象，采用随机数字表法将患者分为A、B、C 3组，每组40例。3组患者均给予麻黄与石膏不同剂量配比的麻杏石甘汤治疗，A组：麻黄：石膏=1：3，B组：麻黄：石膏=1：5，C组：麻黄：石膏=3：8，3组均连续治疗1个月。比较3组治疗后临床症状消失时间、临床疗效及治疗前后肺功能和EOS计数、CRP水平变化。结果：治疗后B组总有效率明显高于A组和C组（P<005）。治疗后B组患者咳嗽、咳痰、气喘症状及肺部罗音消失时间均明显早于A、C 2组（P<005）。与治疗前比较，治疗后3组患者FEV1、FVC及PEmax均明显增加，且B组明显大于A、C 2组（P<005或P<001）。与治疗前比较，治疗后3组患者外周血EOS计数及血清CRP水平均明显降低，且B组明显低于A、C 2组（P<001）。结论：麻杏石甘汤中麻黄：石膏为1：5的配比可更明显地改善肺热喘咳证肺炎患者临床症状，降低炎性反应状态，改善肺通气功能，提高治疗效果，建议临床推广使用。 |
| English Summary: |
| To explore the clinical effects of different dosage ratio of Herba Ephedra and Gypsum Fibrosum in Maxing Shigan Decoction for treating lung heat with panting and cough syndrome.Methods:A total of 120 cases with pneumonia of lung heat with panting with cough syndrome admitted to our hospital from June 2015 to June 2018 were selected and randomly divided into A,B,and C groups,with 40 cases in each group.All of the 3 groups were treated with Maxing Shigan Decoction with different doses of Herba Ephedra and Gypsum Fibrosum.The group A:Herba Ephedra:Gypsum Fibrosum=1:3,the group B:Herba Ephedra:Gypsum Fibrosum=1:5,and the group C:Herba Ephedra:Gypsum Fibrosum=3:8.The 3 groups were treated continuously for 1 month.The disappearance time of clinical symptoms,clinical efficacy after treatment and changes of lung function,EOS count and CRP level before and after the treatment were compared of the 3 groups.Results:After the treatment,the total effective rate of the group B was significantly higher than that of the group A and the group C(P<005).After treatment,the disappearance time of cough,expectoration,asthma symptoms and lung rale in the group B was significantly earlier than that in the group A and C(P<005).Compared with before the treatment,the FEV1,FVC and PEmax were significantly increased of the 3 groups after the treatment,and these in the group B were significantly larger than those in the group A and C(P<005 or P<001).Compared with before the treatment,the EOS count in peripheral blood and the serum level of CRP of the 3 groups were significantly decreased after the treatment,and these in the group B was significantly lower than those in the group A and C(P<001).Conclusion:Maxing Shigan Decoction with Herba Ephedra:Gypsum Fibrosum=1:5 can significantly improve the clinical symptoms of pneumonia of lung heat with panting and cough syndrome,reduce the inflammatory response,improve lung ventilation function,enhance the therapeutic effect,which is recommend to use clinically. |
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