Mongolian medicine and Chinese medicine have different understanding of depression.Mongolian medicine thinks that the depression is caused by the preponderance of Heyi,and the treatment of depression should focus on regulating Heyi,balancing the three roots,tranquilizing heart and calming mind,and promoting the conduction of the white vessel.Chinese medicine thinks that liver depression and qi stagnation as well as emotional disorder are the core pathogenesis of depression,and the treatment should focus on soothing liver and relieving depression,taking heart and spleen into account.Binlang Shisanwei Pills is the classic prescription of Mongolian medicine in regulating Heyi.It has the function of regulating Heyi,calming the mind and relieving pain.By regulating Heyi and balancing the three roots,it promotes the conduction of the white vessel and achieves the purpose of treating depression.Mongolian medicine believes that the brain is the sea of the white vessel,so the heart and the brain being treated together is the mechanism of treating depression in fact.From the point of view of traditional Chinese medicine,it is found that Binlang Shisanwei Pills contains many acrid medicines and can moving qi and warm the middle.So,regulating qi movement of spleen and stomach in the middle energizer may be an important way to treat depression,and the efficacy of warming and supplementing kidney yang also suggests that it regulates heart,brain and kidney together to treat depression.Therefore,in the clinical treatment of depression,Chinese medicine can learn from the experience of Mongolian medicine about its application of acrid medicines,and pay attention to regulating qi movement of spleen and stomach as well as warming and supplementing kidney yang.Chinese medicine treatment of depression is mainly from the liver,so Mongolian medicine can also learn from the experience of Chinese medicine to apply medicines for soothing liver and relieving depression.