世界中医药
文章摘要
蛇六谷抗肿瘤的临床应用与作用机制
An Overview on Clinical Application and Mechanism of Anti-tumor of Amorphophallus Rivieri Durieu
投稿时间:2018-07-06  
DOI:10.3969/j.issn.1673-7202.2019.07.063
中文关键词: 蛇六谷  清热解毒  抗肿瘤  增殖  免疫  细胞毒性
英文关键词: Amorphophallus Rivieri Durieu  Clearing heat and resolving toxins  Anti-tumor  Proliferation  Immunity  Cytotoxicity
基金项目:上海市卫生和计划生育委员会,上海市中医药发展办公室中医优势病种培育项目(21.58.03)
作者单位
邹温园,戈欣,范小秋,龚亚斌 上海中医药大学附属岳阳中西医结合医院肿瘤科上海200437 
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中文摘要:
      蛇六谷作为清热解毒药,在古代、现代的抗肿瘤治疗中都发挥着积极的作用。通过对近几年相关文献学习,从传统、现代临床用药,现代药理作用机制研究等各方面进行综述,发现蛇六谷对毒热瘀积等各类肿瘤都有着一定的临床效果,对肺癌、胰腺癌、乳腺癌、脑癌等作用效果较为显著。其抗肿瘤机制可能与抑制肿瘤细胞的增殖、增强细胞免疫、细胞毒性或抗氧化活性等方面相关。
英文摘要:
      As a drug of clearing heat and resolving toxins,Amorphophallus Rivieri Durieu plays an active role in ancient and modern anti-tumor therapy.Through the study on literature in recent years,literature review is conducted from traditional and modern clinical medication,studies on modern pharmacological mechanism and other aspects.It is found that Amorphophallus Rivieri Durieu is somewhat clinically effective on tumors of toxin-heat stasis and other types.And for lung cancer,pancreatic cancer,breast cancer,brain cancer and other cancers,the efficacy is more significant.Its anti-tumor mechanism may be related to the inhibition of tumor cell proliferation,enhancement of cellular immunity,cytotoxicity or anti-oxidative activity,etc.
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