针灸临床试验中安慰针刺对照的应用现状
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云南省院士(专家)工作站—朱勉生专家工作站项目(2017IC013);云南省重点研发计划项目(国际科技合作)(2018IA059)


Application Status of Placebo-acupuncture Control in Clinical Trials of Acupuncture and Moxibustion
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    摘要:

    随着国内外对于针灸的关注与研究不断增加,针灸的疗效逐渐得到广泛认可,但是也有一些大样本的研究表示针刺疗效与安慰针刺无差异有统计学意义。其主要的原因就是目前尚未有公认的安慰针刺对照方法,这一定程度上影响了针灸的进一步发展。所以本文通过检索国内外文献,总结目前临床研究中常用的安慰针刺对照方法并分析其优缺点,提出改进思路,以期引发对针灸临床试验中安慰针刺设计的进一步思考,开展更加符合针灸特殊性的高质量研究客观评价其疗效。

    Abstract:

    With the increasing attention and research on acupuncture and moxibustion at home and abroad,the efficacy of acupuncture and moxibustion has gradually been widely recognized,but there are also some large sample studies which show that there is no significant difference between the efficacy of acupuncture and placebo acupuncture.The main reason is that there is no accepted method of placebo-acupuncture control,which has affected the further development of acupuncture to a certain extent.Therefore,by searching the domestic and foreign literature,this paper summarizes the commonly used placebo-acupuncture control methods in clinical research,analyses their advantages and disadvantages,and puts forward some improvement ideas,in order to trigger further thinking on the design of placebo-acupuncture in clinical trials of acupuncture and moxibustion,and carry out high-quality research more in line with the specificity of acupuncture and moxibustion to objectively evaluate its efficacy.

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孙俊俊,李云芬,朱勉生.针灸临床试验中安慰针刺对照的应用现状[J].世界中医药,2019,(08).

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  • 收稿日期:2019-06-15
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  • 在线发布日期: 2019-09-10
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