To explore the therapeutic effect of Jianpi Shengxue Tablet on patients with chronic heart failure(CHF)accompanied by anemia and its influence on anemia and inflammatory factors.Methods:A total of 60 patients with CHF accompanied by anemia who visited Xindu District Third People's Hospital from January 2015 to June 2018 were randomly divided into a control group(30 cases)and an observation group(30 cases).All patients were given conventional symptomatic and supportive treatment with western medicine，while the observation group was additionally given Jianpi Shengxue Tablets on this basis of the control group.Both groups of patients were treated continuously for 4 weeks.The curative effect，levels of inflammatory factor，hemoglobin(HGB)，red blood cell(RBC)，serum iron(Fe)and score of quality of life in the 2 groups were observed and compared.Results:The total effective rate in the observation group(8000%)was significantly higher than that in the control group(5333%)(P<005).After treatment，the levels of inflammatory factors interleukin-6(IL-6)，tumor necrosis factor-(TNF-α)and score of Minnesota cardiac insufficiency quality of life scale(MLHFQ)in the 2 groups decreased，and the levels of IL-6，TNF-αand score of MLHFQ in the observation group were lower than those in the control group(P<005).After treatment，the levels of HGB，RBC and Fe in the 2 groups increased，and the levels of HGB，RBC and Fe in the observation group were higher than those in the control group(P<005).Conclusion:On the basis of conventional western medicine treatment，Jianpi Shengxue Tablet has a significant clinical effect on patients with CHF accompanied by anemia.It can better improve the syndrome of heart and kidney yang deficiency，inhibit the secretion of inflammatory factors，control the symptoms of anemia，and improve the cardiac function.It is worthy of further clinical research and application.