| 引用本文:王瑞博，张长江，付卫平，唐晓东.自拟通督健腰汤在退行性腰椎管狭窄症患者经皮全脊柱内镜术后的应用[J].世界中医药,2019,(08):. |
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| 自拟通督健腰汤在退行性腰椎管狭窄症患者经皮全脊柱内镜术后的应用 |
| Application of Self-made Tongdu Jianyao Decoction in Patients with Degenerative Lumbar Spinal Stenosis After Percutaneous Total Spinal Endoscopy |
| 投稿时间：2018-12-14 |
| DOI：10.3969/j.issn.1673-7202.2019.08.040 |
| 中文关键词: 自拟通督健腰汤 经皮全脊柱内镜手术 退行性腰椎管狭窄症 |
| English Keywords:Self-made Tongdu Jianyao Decoction Percutaneous total spinal endoscopy Degenerative lumbar spinal stenosis |
| 基金项目:2016年河南省科技攻关项目（162102310062） |
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| 中文摘要: |
| 目的：探讨在退行性腰椎管狭窄症患者经皮全脊柱内镜术后自拟通督健腰汤的应用价值。方法：选取2016年2月至2018年8月郑州大学第五附属医院收治退行性腰椎管狭窄症患者91例作为研究对象，按照随机数字表法随机分为对照组（n=45）与观察组（n=46），对照组给予经皮全脊柱内镜手术，术后配合给予常规西药；观察组给予经皮全脊柱内镜手术，术后配合给予自拟通督健腰汤。对比治疗前、1个月后症状评分变化，治疗前、2周后和1个月后腰椎功能障碍指数（ODI）评分变化，腰椎功能恢复效果，术后并发症及药物不良反应发生率。结果：治疗后2组下肢麻木、腰部疼痛、步行障碍、感觉障碍症状评分均低于治疗前（P<005），且治疗后观察组症状评分均低于对照组（P<005）；ODI评分组间、时间、交互作用比较，差异均有统计学意义（P<005），且2组2周后ODI评分均低于治疗前（P<005），1个月后ODI评分均低于治疗前和2周后（P<005），2周后、1个月后观察组ODI评分均低于对照组（P<005）；2组腰椎功能效果分布比较，差异有统计学意义（P<005），且观察组腰椎功能恢复优良率明显高于对照组（P<005）；观察组并发症及药物不良反应发生率与对照组比较，差异均无统计学意义（P>005）。结论：对退行性腰椎管狭窄症患者经皮全脊柱内镜术后采用自拟通督健腰汤治疗能够显著减轻症状，改善腰椎功能，且具有较高的安全性。 |
| English Summary: |
| To explore the application value of self-made Tongdu Jianyao Decoction in patients with degenerative lumbar spinal stenosis after percutaneous total spinal endoscopy.Methods:A total of 91 patients with degenerative lumbar spinal stenosis admited in the Fifth Affiliated Hospital of Zhengzhou University from February 2016 to August 2018 were selected as research objects，and they were randomly divided into control group(n=45)and observation group(n=46).The control group was treated with percutaneous total spine endoscopic surgery，combined with conventional western medicine after the operation.The observation group was treated with percutaneous total spinal endoscopic surgery with self-made Tongdu Jianyao Decoction after the operation.Changes of symptom scores before the treatment and after 1 month of the treatment，changes of lumbar dysfunction index(ODI)scores before the treatment，after 2 weeks of the treatment and after 1 month of the treatment，the effect of lumbar functional recovery，and incidences of postoperative complications and adverse drug reactions were compared.Results:After the treatment，the symptom scores of lower limb numbness，lumbar pain，walking disorder and sensory disorder in the 2 groups were lower than those before the treatment(P<005)，and the symptom scores in the observation group after the treatment were lower than those in the control group(P<005).There were significant differences in the ODI scores between the groups，at different time and within interaction(P<005)，and the ODI scores in the 2 groups after 2 weeks were all lower than those before the treatment(P<005).After 1 month，the ODI scores were lower than those before the treatment and after 2 weeks of the treatment(P<005).Either 2 weeks or 1 month after the treatment，the ODI scores in the observation group were lower than those in the control group(P<005).The difference in the effect distribution of lumbar function between the 2 groups was statistically significant(P<005).The good rate of lumbar function recovery in the observation group was significantly higher than that in the control group(P<005).There was no significant difference in the incidences of complications and adverse drug reactions between the observation group and the control group(P>005).Conclusion:The treatment of degenerative lumbar spinal stenosis with self-made Tongdu Jianyao Decoction can significantly relieve symptoms after the percutaneous total spinal endoscopy，improving lumbar spinal function，which has high safety. |
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