To explore the effects of deficiency and excess syndromes in traditional Chinese medicine(TCM)and age factors on autonomic nervous function in patients with coronary heart disease.Methods:From October 2014 to June 2017,150 patients with coronary heart disease(CHD)were selected as research objects from the outpatient and inpatient department of cardiology in Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University and Wangjing Hospital of China Academy of Chinese Medical Sciences.On the basis of the theory of deficiency and excess syndrome differentiation in TCM,the patients were divided into deficiency syndrome group,excess syndrome group and deficiency-excess complex syndrome group.Then the patients were divided into youth group,middle-aged group,young elderly group and elderly group according to the WHO age subsection standard.Heart rate variability(HRV)time domain and frequency domain indexes of patients were collected,and the HRV indexes of different age and syndrome groups of patients were analyzed by multiple linear stepwise regression analysis to evaluate the influence of syndrome and age on HRV.Results:The HRV index SDNN was negatively correlated with age,and RMSSD,TP,LF and HF were negatively correlated with age and syndromes of deficiency and excess.Conclusion:Both TCM syndromes and age have effects on autonomic nervous function.With the syndrome transformation from excess to deficiency and the increase of age,the autonomic nervous function of the patients decreases gradually.