Radix Astragali is a kind of valuable Chinese materia medica commonly used in clinical practice,so it is called “8 of 10 prescriptions using Radix Astragali”.With the idea of prevention before disease onset in traditional Chinese medicine(TCM),Radix Astragali is used as a medicinal and edible medicinal material with increasingly wide application.Ultrafine powder of decoction pieces has attracted wide attention in the pharmaceutical field,and it has become more and more popular in the modern society because of its advantages such as the increase of its dissolved effective composition and convenient use.In this paper,we summarize the research progress of cell wall-broken decoction pieces of Radix Astragali in detail in order to provide a scientific basis for research and development on cell wall-broken decoction pieces of Radix Astragali.