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文章摘要
引用本文:李静1，吕志超2，任宏娜2，孙惠敏2，刘秀玮1.芩连翘皮方联合西药治疗肺炎对患者血常规及炎性因子的影响[J].世界中医药,2019,(10):.  
芩连翘皮方联合西药治疗肺炎对患者血常规及炎性因子的影响
Effects of Qinlian Qiaopi Recipe Combined with Western Medicine on Blood Routine and Inflammatory Factors in Patients with Pneumonia
投稿时间：2019-04-11  
DOI：10.3969/j.issn.1673-7202.2019.10.040
中文关键词:  芩连翘皮方  西药  抗生素  肺炎  中西医结合  疗效  血常规  炎性因子
English Keywords:Qinlian Qiaopi Recipe  Western medicine  Antibiotics  Pneumonia  Integrated traditional Chinese and western medicine  Clinical efficacy  Blood routine  Inflammatory factors
基金项目:河北省中医药管理局科研计划项目（2019221）
作者单位
李静1，吕志超2，任宏娜2，孙惠敏2，刘秀玮1 1 河北省唐山市中医医院西院区，唐山，063000
2 河北省唐山市中医医院，唐山，063000 
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中文摘要:
      目的：探讨芩连翘皮方联合西药治疗肺炎对患者血常规及炎性因子的影响。方法：选取2017年12月至2018年12月唐山市中医医院收治的肺炎患者118例作为研究对象，按照随机数字表法将其分为观察组与对照组，每组59例。对照组应用常规西药进行治疗，观察组在对照组的基础上加用芩连翘皮方治疗，2组均连续治疗2周。统计2组临床疗效及主要中医症状积分变化情况；检测并比较2组治疗前后血常规水平及炎性因子水平。结果：治疗后观察组总有效率为89.83%，显著高于对照组的74.58%（P<0.05）；与治疗前比较，治疗后2组发热、呼吸急促、咳嗽、痰壅及肺罗音等主要中医症状积分均显著下降（P<0.01），且观察组显著低于对照组（P<0.05或P<0.01）；与治疗前比较，治疗后2组WBC、N%、水平均显著下降（P<0.01），且观察组显著低于对照组（P<0.05或P<0.01）；与治疗前比较，治疗后2组血清Hs-CRP、PCT、IL-8及TNF-α水平均显著下降（P<0.05），且观察组显著低于对照组（P<0.05或P<0.01）。结论：芩连翘皮方联合西药治疗肺炎可有效改善患者临床症状，调控其血常规水平，且降低血清炎性因子水平，进而控制病情进展，提升临床疗效。
English Summary:
      To explore the effects of Qinlian Qiaopi Recipe combined with western medicine on blood routine and inflammatory factors in patients with pneumonia.Methods:A total of 118 cases patients with pneumonia treated in Tangshan Traditional Chinese Medicine Hospital from December 2017 to December 2018 were selected as the study objects,and were divided into an observation group and a control group according to the random number table method,with 59 cases in each group.The control group was treated with routine western medicine,and the observation group was treated with Qinlian Qiaopi Recipe on the basis of control group,and 2 groups were treated for 2 weeks continuously.The clinical curative effect and the change of symptom integral in main traditional Chinese Medicine(TCM)of 2 groups were statisticsed; the blood routine and inflammatory factor levels of the 2 groups before and after treatment were detected and compared before and after treatment.Results:After treatment,the total effective rate in the observation group was 89.83%,which was significantly higher than the 74.58% in the control group(P<0.05); Compared with before treatment,the scores of TCM symptoms such as fever,shortness of breath,cough,phlegm and lung rales in the 2 groups after treatment significantly decreased(P<0.01); and the observation group was significantly lower than the control group(P<0.05 or P<0.01); Compared with before treatment,the WBC,N%,L% levels decreased significantly in the 2 group after treatment(P<0.01),and the observation group was significantly lower than the control group(P<0.05 or P<0.01); Compared with before treatment,the levels of serum Hs-CRP,PCT,IL-8 and TNF-α in the 2 groups decreased significantly(P<0.05),and those in the observation group were significantly lower than those in the control group(P<0.05 or P<0.01).Conclusion:The treatment of pneumonia with Qinlian Qiaopi Recipe and western medicine can effectively improve the clinical symptoms,regulate the level of blood routine,reduce the level of serum inflammatory factors,and then control the progress of the disease and improve the clinical efficacy.
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