世界中医药
文章摘要
引用本文:黄佳钦,曹云,符欣,常炳龙,何莹,林稼樱,张忠绵,张婧,李志红.基于数据挖掘探讨肝胃郁热型吞酸病用药规律[J].世界中医药,2019,(11):.  
基于数据挖掘探讨肝胃郁热型吞酸病用药规律
Discussion on Medication Rule for Acid Reflux of Heat Stagnation in the Liver and Stomach Syndrome Based on Data Mining
投稿时间:2018-12-17  
DOI:10.3969/j.issn.1673-7202.2019.11.022
中文关键词:  中药复方  肝胃郁热  吞酸  用药规律  数据挖掘  聚类分析  因子分析  田德禄教授  “清降”理论
English Keywords:Chinese herbal compound  Heat stagnation in the liver and stomach  Acid reflux  Medication rule  Data mining  Cluster analysis  Factor analysis  Professor Tian Delu  ”Clearing and descending” theory
基金项目:全国名老中医药专家传承工作室建设项目;北京中医药“薪火传承3+3工程”建设项目;吴阶平医学基金会临床科研专项资助项目(320.6750.17233)
作者单位
黄佳钦,曹云,符欣,常炳龙,何莹,林稼樱,张忠绵,张婧,李志红 北京中医药大学东直门医院北京100700 
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中文摘要:
      目的:基于数据挖掘技术探讨中药复方治疗肝胃郁热型吞酸的用药规律。方法:以中国方剂数据库为检索库,检索治疗“吞酸”的中药方剂,再根据方剂主治及功效筛选治疗肝胃郁热型吞酸的方剂,并采用Excel、SPSS 20.0软件进行频数及频率分析、因子分析。结果:中药复方治疗吞酸涉及复方291首,治疗肝胃郁热型吞酸涉及69首,中药107种,高频中药25味,陈皮、甘草、木香、砂仁、青皮和厚朴较为常用;在功效方面,理气药、化湿药、活血化瘀药、消食药及清热药选用次数均较多。五味以辛、苦为主;归经以脾经、胃经、肝经选用次数较多。因子分析最后提取了7组影响肝胃郁热型吞酸的药物组合因子;通过聚类分析,提取了8个常用的药对或药组。结论:该研究结果与田德禄教授应用“清降”法治疗吞酸的学术思想有许多相似之处。
English Summary:
      Based on data mining technology,to explore the medication rules of traditional Chinese medicine(TCM)compound treatment of acid reflux,which syndrome is heat stagnation in the liver and stomach.Methods:Taking the Chinese prescription database as the retrieval database,the traditional Chinese medicine(TCM)prescription for treating acid reflux was searched.The prescriptions for the treatment of heat stagnation in the liver and stomach was selected according to the efficacy,and Excel,SPSS 20.0 software was used for frequency analysis and factor analysis.Results:Chinese herbal compound treatment of acid reflux involved 291 prescriptions,which used for heat stagnation in the liver and stomach syndrome were 69,107 kinds of Chinese medicine,25 flavors of high frequency herbs,Pericarpium Citri Reticulatae,Radix Glycyrrhizae,Radix Aucklandiae,Fructus Amomi Villosi,Pericarpium Citri Reticulatae Viride and Cortex Magnoliae Officinalis were commonly used.In the aspect of efficacy,qi regulating herbs,resolving dampness herbs,activating blood and resolving stasis herbs,eliminating food herbs and clearing heat herbs were most commonly used.Herbs with pungent and bitter tastes were commonly used; the meridian of spleen,stomach and liver were most commonly chosen; 7 groups of affecting heat stagnation in the liver and stomach syndrome were extracted; 8 drug groups were obtained by cluster analysis.Conclusion:The results of this study have many similarities with Professor Tian Delu's application of the "clearing and descending" method to treat acid reflux.
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