| 引用本文:刘晓彤，刘晓婷，刘金响，杨娜，叶峥嵘.阳和汤治疗肿瘤的系统评价与Meta分析[J].世界中医药,2019,(12):. |
|
| 阳和汤治疗肿瘤的系统评价与Meta分析 |
| Systematic Review and Meta-analysis of Yanghe Decoction in Treating Tumor |
| 投稿时间：2018-12-29 |
| DOI：10.3969/j.issn.1673-7202.2019.12.026 |
| 中文关键词: 阳和汤 肿瘤 系统评价 Meta分析 循证医学 中医药 癌症 辅助治疗 |
| English Keywords:Yanghe Decoction Tumor Systematic review Meta-analysis Evident-based medicine Traditional Chinese medicine Cancer Adjuvant treatment |
| 基金项目:陕西省教育厅科学研究项目（17JK0204）;陕西省中医管理局中医药科研课题（JCMS073）;咸阳市科学技术研究计划项目（2017k02-93） |
|
| 摘要点击次数: 454 |
| 全文下载次数: 453 |
| 中文摘要: |
| 目的：评价阳和汤治疗肿瘤的临床疗效与安全性。方法：全面检索2018年10月以前CNKI、维普、万方、pubmed、中国生物医学文献数据库等数据库,筛选随机对照试验（Randomized Controlled Tests,RCTs），采用RevMan 5.3软件对纳入的研究资料进行Meta分析，用Jadad量表评价文献质量。结果：共纳入6篇临床资料，Meta分析结果示：总有效率：RR=1.46 95% CI=［1.22,1.74］，Z=4.23,P<0.05，I2=0%，表明阳和汤或阳和汤联合放化疗治疗肿瘤效果优于单纯使用放化疗手段；阳和汤治疗肿瘤过程中，不良反应多为放化疗引起的患者不适，包括恶心呕吐、食欲减退等。结论：阳和汤观察组可显著提高患者生存、生命质量，减轻患者痛苦。但本系统评价存在一定的发表偏倚。考虑纳入文献质量较低，实验设计存在缺陷仍需大量严谨的临床随机对照试验进行验证。 |
| English Summary: |
| To evaluate the clinical efficacy and safety of Yanghe Decoction in treating tumor.Methods:All the papers published before October 2018 from databases such as Chinese National Knowledge Infrastructure(CNKI)，Vip，Wanfang database，PubMed and China Biology Medicine(CBM)were retrieved，and randomized controlled trials(RCTs)were screened.Meta-analysis on the selected study materials was conducted with RevMan 5.3 software，and Jadad scale was used to evaluate the quality of these papers.Results:A total of 6 clinical materials were included.The meta-analysis showed：total effective rate：RR=1.46，95% CI=［1.22，1.74］，Z=4.39，P<0.05，I2=0%，which revealed that the efficacy of Yanghe Decoction or Yanghe Decoction combined with chemoradiotherapy in treating tumor were superior to using chemoradiotherapy alone.The adverse reaction in the process of using Yanghe Decoction to treat tumor was mostly discomfort caused chemoradiotherapy，including nausea，vomiting，anorexia，and so on.Conclusion:The Yanghe Decoction treatment group can remarkably improve patients' survival quality and life quality and relieve patients' pain.But this systematic review had some kind of publication bias.The quality of the included papers is relatively low.The experimental design had defects and a large amount of serious clinical RCTs are still needed to verify the results. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
