世界中医药

目的：分析连花清瘟颗粒治疗新型冠状病毒肺炎的临床疗效。方法：选取2020年1月1—31日在武汉科技大学附属普仁医院就诊的，应用连花清瘟颗粒联合常规治疗（根据病情监测给予营养支持治疗、抗病毒治疗及抗菌药物治疗等）的新型冠状病毒肺炎患者54例作为研究对象。结果：应用连花清瘟颗粒治疗3 d后，发热、乏力、咳嗽症状消失率分别为47.5%、35.1%、20.0%，治疗5 d后发热、乏力、咳嗽症状消失率分别为62.5%、59.5%、50.0%，治疗7 d后发热、乏力、咳嗽症状消失率分别为80.0%、75.7%、76.7%；发热、乏力、咳嗽消失天数分别为（3.6±2.14)d、（4.1±2.58)d、（5.3±2.63)d；治疗7 d后，其他症状体征（胸闷、呼吸困难、湿啰音）消失率分别为84.6%、100%、89.5%；有效率为81.6%，且临床应用安全性良好。结论：连花清瘟颗粒明显改善新型冠状病毒肺炎普通型患者发热、咳嗽、乏力等症状，减少发热、乏力、咳嗽持续天数，为临床治疗该病提供初步研究证据。

English Summary:

To analyze the clinical effectiveness of Lianhuaqingwen Granules(LH-C)novel coronavirus pneumonia（NCP）patients.Methods:The clinical data of 54 ordinary NCP patients were retrospectively analyzed at the Puren affiliated Hospital of Wuhan University of Science and Technology.Results:After treatment with LH-C for three consecutive days,the rate of symptoms disappearance in fever,weakness,and cough was 47.5%,35.1%,and 20%,respectively.Five days later,the rate of symptoms disappearance in fever,weakness,and cough increased to 62.5%,59.5%,and 50.0%,respectively.By the seventh day,the rate of symptoms disappearance in fever,weakness,and cough reached 80.0%,75.7%,and 76.7%.The days of symptoms disappearance in fever,weakness,and cough was （3.6±2.14）d,（4.1±2.58）d,and（5.3±2.63）d.As regards the other symptom,the rate of symptoms disappearance in the chest stuffiness,the dyspnea,and the moist crackles was 84.6%,100%,and 89.5%,and the total efficiency was up to 81.6% without any observed side effects by the seventh day.Conclusion:LH-C could significantly relieve clinical symptoms in ordinary NCP patients by inhibiting fever,weakness,and cough,and reducing their duration.All these results provided preliminary clinical evidence for LH-C in the NCP treatment.

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