| 引用本文:杨涛1，崔人匀1，刘寰宇1，郝力争1，陈健1，安炯俊1，李忠2.基于中医经典理论探索新型冠状病毒肺炎治疗策略及麻黄升麻汤为主方的可行性分析[J].世界中医药,2020,(02):. |
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| 基于中医经典理论探索新型冠状病毒肺炎治疗策略及麻黄升麻汤为主方的可行性分析 |
| Exploration of Traditional Chinese Medicine treatment strategy for 2019-nCov Infected Pneumonia and Feasibility of Mahuang Shengma Decoction Based on TCM Classical Theory |
| 投稿时间：2020-02-12 |
| DOI：10.3969/j.issn.1673-7202.2020.02.008 |
| 中文关键词: 新型冠状病毒 新型冠状病毒肺炎 瘟疫 麻黄升麻汤 肺热脾寒 寒热错杂 五运六气 网络药理学 |
| English Keywords:2019-nCov Novel Coronavirus Pneumonia Plague Mahuang Shengma Decoction The lung heat and spleen cold Intertwist of cold with heat Five movements and six climates Network pharmacology |
| 基金项目:北京市科技计划“十病十药”研发项目(Z161100001816014) |
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| 中文摘要: |
| 新型冠状病毒肺炎(NCP)具有极强的流行性和传染性,临床主要表现为发热、干咳、乏力,重症者可有呼吸困难,严重者则快速进展为呼吸窘迫综合征、脓毒症休克等,甚至死亡。我们综合相关报道和一线临床资料,结合中医温病理论,认为本病属中医“瘟疫”范畴,病机特点在于寒热错杂,本虚标实。其致病因素包括“寒”“热”“湿”,主要病位在“肺”和“肝”,涉及脾肾。其传变速度快,临床多出现肝肾亏虚,肺热脾寒、木火刑金,呈寒热错杂之象。依据本病的病机特点,我们提出了不同阶段的中医治疗方案和用药策略。同时,分析了麻黄升麻汤为主方加减治疗NCP的可行性预测。我们认为麻黄升麻汤清上温下,表里同治,兼顾肺、脾、肝、肾,具有温、清、宣、补等功效,符合NCP的中医症候学特点,为疫情的临床防治提供参考。 |
| English Summary: |
| Novel coronavirus pneumonia(NCP)is a disease of highly epidemic and infectious.The main clinical manifestations of NCP are fever,dry cough and fatigue.Severe cases can have dyspnea,and critical cases rapidly progress to respiratory distress syndrome,septic shock,and even death.Based on the relevant clinical reports and the first-line data,combined with the theory of TCM Febrile Disease,it is considered that NCP belongs to the category of “Plague” in TCM,and the pathogenesis is characterized by the intertwist of cold with heat,root deficiency and branch excess.The main pathogenic factors are “Cold”,“Heat” and “Dampness”,mainly located in “Lung” and “Liver”,involving “Spleen” and “Kidney”.Its transmission speed is fast,and its clinical manifestations are as follows: the liver and kidney are deficient due to the injury of Yin and Yang,the lung heat and spleen cold,the wood fire punishes the gold,and the cold and heat are intertwisted.According to the characteristics of the pathogenesis of NCP,this paper proposed different stages of TCM treatment plan and medication strategy.At the same time,this paper analyzes the feasibility of Mahuang Shengma decoction as the main prescription in the treatment of NCP.We believe that Mahuang Shengma decoction has the functions of clearing upper jiao and warming the lower jiao,simultaneous treatment of exterior and interior,while the treatment refers to the lung,spleen,liver and kidney.In a word,it has the functions of warming,clearing,promoting and tonifying.It conforms to the characteristics of TCM Syndromes of NCP and provides reference for clinical prevention and treatment of epidemic situation. |
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