Iris tectorum Maxim.(Chuan Shegan)is traditional Chinese Medicine commonly used to treat pharyngitis and laryngitis for a long time in China, which was documented in Chinese Pharmacopoeia(2005). In recent years, fundamental research and new TCM or the related formula of Iris tectorum Maxim. have been got more attention. In this paper, we summarized and analyzed the fundamental research and clinical application of Iris tectorum Maxim， including its origin, ancient studies, chemical constituents, pharmacology and clinical application, in order to provide new ideas for the further research and development of Iris tectorum Maxim.