| 引用本文:周琪1，雷乾娅1，赵军宁2，方清茂2，王曙1.川产道地药材川贝母(栽培品)鉴别与品质研究[J].世界中医药,2020,(02):. |
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| 川产道地药材川贝母(栽培品)鉴别与品质研究 |
| Identification and Quality Research on Fritillariae Cirrhosae Bulbus(Cultivation)of Sichuan Dao-di Herbs |
| 投稿时间：2020-01-09 |
| DOI：10.3969/j.issn.1673-7202.2020.02.018 |
| 中文关键词: 川贝母 瓦布贝母 暗紫贝母 太白贝母 松贝栽培品 青贝栽培品 性状 薄层鉴别 含量测定 |
| English Keywords:Fritillariae Cirrhosae Bulbus Fritillaria unibracteata var. Wabuensis F.unibracteata F taipaiensis Cultivated Songbei Cultivated Qingbei TLC identification Content determination |
| 基金项目:国家中医药管理局国家中药标准化项目(ZYBZH-Y-SC-40);2018全国中药资源普查项目(财社[2018]43号);四川省中医药管理局科研项目(2017Z004) |
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| 中文摘要: |
| 目的:对川贝母最新试验研究结果进行描述,为川贝母药材鉴别方法提供一定提升思路。方法:用性状观察,薄层色谱研究,含量测定方法对川贝母药材特点进行详细描述。结果:1)栽培品与野生川贝母在性状方面的区别主要在于栽培品鳞叶表面的颜色偏黄,有皱缩,稍粗糙,青贝的个体较大(可达4 cm);2)实际上市的栽培品中具松贝性状特征的,主要源于暗紫贝母,具青贝性状特征的主要源于川贝母、瓦布贝母和太白贝母;3)川贝母的薄层色谱特征主要与植物基源有关,有效成分结构类型相似但细微结构有差异;4)具有松贝特征的栽培品与具有青贝特征的栽培品的总生物碱含量有明显差异。结论:建议将川贝母“栽培品”细分为“松贝栽培品”和“青贝栽培品”2种规格以便市场管理和临床应用,对川贝母薄层色谱鉴别方法和现行标准中总生物碱含量限度提出了修订建议。 |
| English Summary: |
| To describe the latest experimental research results of Fritillariae Cirrhosae Bulbus, and to provide some thoughts for improving the identification methods of it. Methods:With observation of character, thin layer chromatography research, content determination method, the characteristics of Fritillariae Cirrhosae Bulbus was described in detail. Results:1)In characteristics, the main differences between cultivated product and wild Fritillariae Cirrhosae Bulbus were that the surface of the scales of the cultivated Fritillariae Cirrhosae Bulbus was yellowish, with shrinkage, slightly rough, and the size of Qingbei was larger(up to 4 cm).2)Among the actually cultivated Fritillariae Cirrhosae Bulbus in market, those with Songbei characteristics were mainly derived from Fritillaria unibracteata Hsiao et K. C. Hsia; those with Qingbei characteristics were mainly from Fritillaria cirrhosa D. Don, Fritillaria unibracteata Hsiao et K. C. Hsiavar. wabuensis(S. Y. Tang et S. C. Yue)Z. D. Liu, S. Wang et S. C. Chen and Fritillaria taipaiensis P. Y. Li.3)The TLC identification test showed that the chromatographic characteristics were mainly related to plants origin, indicating that the structure types of the active ingredients of Fritillariae Cirrhosae Bulbus were similar, but the microstructures were different.4)The content determination results showed the significant difference in total alkaloid content between cultivated Fritillariae Cirrhosae Bulbus with Songbei characteristics and with Qingbei characteristics. Conclusion:It is recommended to subdivide the “cultivated Fritillariae Cirrhosae Bulbus” into “cultivated Songbei” and “cultivated Qingbei” for market management and clinical application; Amendments were proposed to the method of TLC identification and the limits of total alkaloids in current standards of Fritillariae Cirrhosae Bulbus. |
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