| 引用本文:王怡菲1，邱模炎1，裴颢2，闫二萍1，张琼英3，刘淑娟4，邹浩5，熊莉莉5，叶钢福3，文天才6.中医药辨治新型冠状病毒肺炎的组方及用药规律探析[J].世界中医药,2020,(03):. |
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| 中医药辨治新型冠状病毒肺炎的组方及用药规律探析 |
| Analysis on the Prescription and Medication Law of Traditional Chinese Medicine Against the Novel Coronavirus Pneumonia |
| 投稿时间：2020-02-22 |
| DOI：10.3969/j.issn.1673-7202.2020.03.008 |
| 中文关键词: 新型冠状病毒肺炎 中医药 诊疗方案 用药规律 描述性统计 |
| English Keywords:Coronavirus Disease 2019 Traditional Chinese Medicine Diagnosis and treatment plan The law of medication Descriptive statistics |
| 基金项目: |
| 作者 | 单位 | | 王怡菲1，邱模炎1，裴颢2，闫二萍1，张琼英3，刘淑娟4，邹浩5，熊莉莉5，叶钢福3，文天才6 | 1 中国中医科学院望京医院,北京,100102
2 中国医药科技出版社,北京,100082
3 厦门市中医医院,福建，361000
4 北京市朝阳区孙河社区卫生服务中心,北京,100015
5 北京中医药大学,北京,100029
6 中国中医科学院中医临床基础医学研究,北京,100700 |
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| 中文摘要: |
| 目的:通过对国家、各省、自治区和直辖市的中医诊疗方案进行整理、分析,探索中医药诊治新型冠状病毒肺炎(COVID-19)的证候、组方及用药规律,以期为临床中医药诊治COVID-19的选方用药提供参考。方法:尽可能全面的检索2020年2月20日之前中文数据库,国家及各省、自治区、直辖市卫生健康委员会、中医药管理局及网页中的相关COVID-19中医药诊疗方案。采用描述性统计方法对诊疗方案中的分期、证候、方剂、中药进行统计分析,并应用Liquorice、Gephi软件分析分期用药分布,进一步探析COVID-19的组方和用药规律。结果:本研究共纳入1个国家COVID-19诊疗方案及26个省、自治区、直辖市的COVID-19中医药诊疗方案(共计27个)。临床最常见的是以初期、中期、重症期、恢复期为分期标准,频次最高的证型为内闭外脱证,使用次数最多的方剂为麻杏石甘汤,使用频次最高的药物是甘草,在疾病初期苍术与麻黄合用的频次最高,在疾病中期石膏与麻黄合用频次最高,在疾病后期半夏与砂仁合用的频次最高。结论:总体来说,各诊疗方案在辨证、选方、用药等方面存在很多共性,证候、方药分布具有一定的规律,但由于气候、地域、体质、饮食习惯等诸多因素的影响,疾病的病性、临床症状也就各有不同,因此在对COVID-19的诊疗中,还需根据具体情况,辨证论治。 |
| English Summary: |
| The syndrome，prescription and medication rule of TCM against the novel coronavirus pneumonia(NCP) were explored by retrieving and analyzing the national，provincial，municipal and autonomous regions' TCM diagnosis and treatment plans.It is expected to provide reference for the TCM medication and treatment for NCP.Methods:Diagnosis and treatment plans of National，provincial，municipal and autonomous regions' Health Commission and Administration of Traditional Chinese Medicine from webpage and Chinese database before February 20，2020 were retrieved.Descriptive statistical method was used to analyze the stages，syndromes，prescriptions and herbs in the diagnosis and treatment plan，Liquorice and Gephi software were used to analyze the distribution of herb by stages，so as to further explore the prescription and medication rules against NCP.Results:One national，26 provincial，municipal and autonomous regions' NCP diagnosis and treatment plan (a total of 27) were included.The most commonly seen clinical staging criteria were early stage，metaphase，severe stage，recovery stage，the highest frequency of syndrome was internal block and external desertions，the most frequently used prescription was Maxing Shigan decoction and the most used drug was liquorice root.atractylodes rhizome and ephedra was the most used combined drugs in the early stage，gypsum and ephedra was the most used combined drugs in the metaphase，pinellia tuber and villous amomum fruit was the most used combined drugs in the late stage.Conclusion:Generally speaking，there are many commonalities in syndrome differentiation，prescription，medication and so on，the distribution of syndrome and prescription has certain rules，but due to the influence of climate，region，physique，eating habits and many other factors，the nature of disease and clinical symptoms are also different，so in the diagnosis and treatment of NCP，syndrome differentiation should be emphasized. |
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