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文章摘要
引用本文:许伟，白明，苗明三.基于数据挖掘探讨中药外用治疗带状疱疹用药规律[J].世界中医药,2020,(03):.  
基于数据挖掘探讨中药外用治疗带状疱疹用药规律
Exploration on Medication Rules of External Use of Chinese Materia Medica in Treating Herpes Zoster Based on Data Mining
投稿时间：2020-01-10  
DOI：10.3969/j.issn.1673-7202.2020.03.015
中文关键词:  带状疱疹  外用  中药  外治  中药复方  配伍规律  数据挖掘  关联规则
English Keywords:Herpes zoster  External use  Chinese materia medica  External treatment  Chinese herbal compound  Compatibility law  Data mining  Association rules
基金项目:河南省产学研项目（182107000029）；国家国际合作基地（2016-65）；国家中医药管理局中医药标准化专项（2017-149-11）
作者单位
许伟，白明，苗明三 河南中医药大学，郑州，450006 
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中文摘要:
      目的：基于数据挖掘分析探讨中药外用治疗带状疱疹的用药规律。方法:以中国知网数据库为检索库，以“SU=‘带状疱疹’and FT=‘中药’*‘外用’”为主题进行高级检索，锁定搜索年限2010年1月1日至2019年12月1日的期刊文献，建立中药外用治疗带状疱疹数据库，并采用Excel、Clementine12.0统计软件对检索结果进行筛选分析，进而分析探讨中药外用治疗带状疱疹的用药规律及其可能机制。结果:近10年中国知网共有中药外用治疗带状疱疹涉及复方116首，共涉及中药184种，高频中药52味，冰片、大黄、雄黄、黄柏等应用较多；四气以寒、温，五味以辛、苦，归经以肝、心、脾为主；清热药与活血化瘀药在中药外用治疗带状疱疹中应用较多；关联分析共得出药对16条，其中以黄柏→大黄、冰片→雄黄等为常用。结论:中药外用治疗带状疱疹应多应用寒、温、辛、苦类中药，以清热与活血化瘀为治疗原则选取相应的中药进行治疗。
English Summary:
      To analyze and explore medication rules of external use of Chinese materia medica in treating herpes zoster based on Data Mining.Methods:CNKI database was taken as retrieval database,with “SU = ‘herpes zoster’ and FT = ‘Chinese materia medica’ * ‘external use’” as the theme for advanced retrieval.Journal literature within fixed number of years for retrieval(January 1,2010 to December 1,2019)was selected.A database of Chinese materia medica in external treatment of herpes zoster was established.Retrieval results were screened out and analyzed by Excel and Clementine 12.0 software,and then medication rules and its possible mechanism of Chinese materia medica in the external treatment of herpes zoster were analyzed and explored.Results:In the past 10 years,a total of 116 compound prescriptions of Chinese materia medica were involved in the external treatment of herpes zoster in CNKI,involving a total of 184 kinds of Chinese materia medica,among which 52 kinds of Chinese materia medica were of high frequency.Borneolum Syntheticum,Radix et Rhizoma Rhei,Realgar,Cortex Phellodendri,etc.were frequently used.Four nature was mainly cold and warm; five flavors were mainly pungent and bitter; and channel tropism was mainly liver,heart and spleen.Heat-clearing medicines and blood-activating and stasis-removing medicines were widely used in the external treatment of herpes zoster by Chinese materia medica.A total of 16 medicine pairs were obtained by association analysis,among which Cortex Phellodendri-Radix et Rhizoma Rhei,Borneolum Syntheticum-Realgar,etc.were commonly used.Conclusion:In the external treatment of herpes zoster by Chinese materia medica,cold,warm,pungent and bitter medicines should be applied more.Corresponding Chinese materia medica should be selected for treatment,according to the principle of clearing heat,activating blood circulation and removing stasis.
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