| 引用本文:王学谦，郑佳彬，关靓，程倩雯，袁嘉萌，林洪生.中医综合治疗方案对肺癌术后患者生命质量及心理状态干预的临床研究[J].世界中医药,2020,(03):. |
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| 中医综合治疗方案对肺癌术后患者生命质量及心理状态干预的临床研究 |
| Clinical Study on Intervention of Comprehensive Treatment of Traditional Chinese Medicine on Quality of Life and Psychological State of Postoperative Patients with Lung Cancer |
| 投稿时间：2018-08-21 |
| DOI：10.3969/j.issn.1673-7202.2020.03.033 |
| 中文关键词: 非小细胞肺癌 术后 中医 生命质量 焦虑 抑郁 综合治疗方案 临床研究 |
| English Keywords:Non-small cell lung cancer Postoperative Traditional Chinese medicine Quality of life Anxiety Depression Comprehensive therapy scheme Clinical study |
| 基金项目:中医药行业科研专项(201307006) |
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| 中文摘要: |
| 目的：探讨中医综合治疗方案对非小细胞肺癌术后患者生命质量、心理状态以及临床症状改善的临床疗效。方法：采用多中心、大样本队列研究方法，选取2014年5月至2016年8月全国14家医院收治的I-IIIa期非小细胞肺癌术后或完成辅助治疗患者503例作为研究对象，其中观察组266例，对照组237例。观察组采用辨证汤药、运动调养、心理调养、饮食调养、功能调养、膏方调养综合治疗方案，对照组仅随访观察。研究2组患者的生命质量、焦虑抑郁状态、临床症状以及不良反应情况。结果：生命质量用FACT-L4.0量表评价，观察组和对照组第1个疗程后评分为（101.60±13.19）分和（91.00±14.29）分，第2个疗程评分为（105.00±13.42）分和（88.60±15.44）分，差异均有统计学意义（P<0.05）；焦虑状态评价用SAS焦虑量表，抑郁状态评价用SDS抑郁量表，2个量表均提示第1个疗程和第2个疗程后观察组疗效均优于对照组，差异有统计学意义（P<0.05）；临床症状评价，提示观察组疗效均优于对照组，差异有统计学意义（P<0.05）。2组均未见不良反应发生。结论：中医综合治疗方案可以提高患者生命质量、改善患者焦虑抑郁状态、改善患者临床症状，是一种值得推广、安全有效的中医康养治疗方案。 |
| English Summary: |
| To observe the clinical efficacy of the comprehensive treatment scheme of traditional Chinese medicine on quality of life，psychological status and clinical symptoms of patients with non small cell lung cancer（NSCLC）after operation.Methods:In the multi-center，large-sample cohort study，a total of 503 patients with I-IIIa NSCLC or completing adjuvant therapy were adopted.Among them，266 were in the experimental group and 237 were in the control group.The patients in the experimental group were treated with the comprehensive treatment methods，namely，dialectical decoction，sports rehabilitation，psychological rehabilitation，dietary rehabilitation，functional rehabilitation，paste rehabilitation.The patients in the control group were treated with observation.Clinically，quality of life，anxiety and depression，TCM symptoms score and side effects were studied in the 2 groups of patients.Results:FACT-L4.0 scale evaluation was used to evaluate the quality of life.After one course of treatment，the scores were(101.60±13.19)and(91.00±14.29)（P<0.05）.After 2 course of treatment，the scores were(105.00±13.42)and(88.60±15.44)，and the differences are statistically significant（P<0.05）.SAS anxiety scale was used to evaluate the anxiety and SDS depression scale was used to evaluate the depression.The 2 scales indicated that the efficacy of the experimental group was better than that of the control group after the first and second courses，with significant difference（P<0.05）.TCM symptoms score indicated that the efficacy of the treatment group was better than that of the control group（P<0.05）.No adverse reactions occurred in the 2 groups.Conclusion:TCM comprehensive treatment scheme can improve the quality of life of patients，the state of anxiety and depression，and the clinical symptoms of patients.It is a worthy of promotion，and is a safe and effective treatment regimen of traditional Chinese medicine cultivation. |
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