To establish the quality standard of Majing Granule.Methods:The contents of ephedrine，baicalin and glycyrrhizic glycoside were measured by HPLC.The HPLC fingerprint of Majing Granules was established.Results:There was a good linear relationship of ephedrine hydrochloride in the range of 0.289 2～2.892 0 μg(r=0.999 9).There was a good linear relationship of baicalin in the range of 0.208 0~2.080 0 μg(r=0.999 9).There was a good linear relationship of liquiritin in the range of 0.192 0~1.920 0 μg(r=0.999 9).The HPLC fingerprint of Majing granules was preliminarily established，and the similarity was above 0.96.A total of 12 common peaks were identified in 10 batches of samples，and 5 of them were identified.Conclusion:This method is stable，accurate and reliable，which can provide the basis for the quality control of Majing Granule.