Shengjiang Powder was originated from the famous doctor YANG Lishan in the book named Shanghan Wenyi Tiaobian from Qing Dynasty.It was once used as a prescription for treating epidemic febrile disease.Professor ZHAO Jinxi believes amassment of stagnated heat，dampness turbidity and pathogenic toxin are the key pathogenesis of this treatment.He believes that its clinical application indications of Shenjiang Power include fever，dizziness，nausea，vomiting，chest distress，constipation and rapid pulse.Meanwhile，the key points of the syndrome differentiation and disease were emphasized.The treatment is made with the flexibility of the syndromes.Now，the preliminary discussion are made on the pathogenesis，source，indications and clinical application of Sheng jiang Powder.