To analyze and summarize the clinical characteristics and medication patterns of common and severe COVID-19 patients in centralized treatment base of Wanzhou District of Chongqing.Methods:The epidemiology, symptomatology, auxiliary examination index and traditional Chinese medicine data of HIS were extracted, the database was built, relevant indicator frequency and correlation were analyzed.Results:The new coronavirus pneumonia is dominated by imported cases, accounting for 89.33%.The most common symptoms are cough (64.89%), fever (59.11%), insomnia (29.78%), expectoration (23.56%), anorexia (21.34%), and fatigue (18.67%).Decreased lymphocyte count, decreased CD4+ and CD8+ counts, decreased albumin, and increased hypersensitivity CRP, especially in severe cases.Among them, lymphocyte count, CD4+, and CD8+ counts are negatively correlated with disease severity.Hypersensitive C-reactive protein is positively correlated with the severity of the disease.Albumin has a declining trend within 1 week after admission.About 50% of cases have chest CT progress to varying degrees within 1 week, which is positively correlated with albumin levels.195 cases of Chinese medicine intervention, 87% participation rate, 345 cases of Chinese medicine intervention, the main forum were Maxing Shigan Decoction(20.29%), Shashen Maidong Decoction(13.62%), Sanren Decoction(10.14%), Qianjing Weijing Decoction(9.85%), Huopo Xialing Decoction(8.4%), the usage were basically consistent with symptomatic performance.Conclusion:COVID-19 is generally susceptible, mostly in the elderly, and the centralized treatment base in Wanzhou is mainly imported.lymphocyte count,CD4,CD8,and high sensitive CRP can be used as disease severity indicators, and albumin and chest CT can be used as disease progression prediction indicators.COVID-19 core pathogenesis of traditional Chinese medicine is summarized as “dampness, heat,toxin and deficiency”, and the main treatment principle is “ventilating lung Qi for dissipating dampness, clearing heat and removing toxicity ,supplementing Qi and nourishing Yin”.