世界中医药
文章摘要
引用本文:王品一1,樊炜静1,金潇2,付常庚2,邢彤2,原方1,王前1,杨宝钟2.孙思邈与叶天士治疗水肿用药规律的比较研究[J].世界中医药,2020,(06):.  
孙思邈与叶天士治疗水肿用药规律的比较研究
Comparison between SUN Simiao and YE Tianshi in Treatment of Edema Disease
投稿时间:2019-03-24  
DOI:10.3969/j.issn.1673-7202.2020.06.009
中文关键词:  水肿  用药规律  中医传承辅助平台  孙思邈  叶天士
English Keywords:Edema disease  Application laws of TCM  Medication characteristics  SUN Simiao  YE tianshi
基金项目:北京市生物医药与生命科学创新培育研究资助项目(Z151100003915132)
作者单位
王品一1,樊炜静1,金潇2,付常庚2,邢彤2,原方1,王前1,杨宝钟2 1 北京中医药大学北京100029
2 北京中医药大学东方医院北京100078 
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中文摘要:
      目的:水肿患者多病情缠绵,中医在治疗水肿病方面存在独特优势,总结中医对此证的经验心得独具临床意义。方法:本次研究通过中医传承辅助平台系统,对孙思邈和叶天士治疗水肿的遣方用药进行统计,如药物剂量、使用频次、四气、五味等,对其进行分析并比较两者之间的异同。结果:孙思邈水肿处方共86首,含中药154味;叶天士用方共91首,含中药136味,其中五味属性上孙、叶2人所用药物皆是辛、甘、苦味药为主,四气属性:二者使用寒药频次有显著不同,孙氏温药(44%)、寒药(31%),叶氏温药(48%)、寒药(22%);治法方面孙氏用利水法61次(45%)、温阳法23次(17%)、活血法13次(10%)、祛湿法10次(7%)、攻逐法29次(21%),叶氏用利水法57次(46%)、温阳35次(28%)、活血5次(4%)、祛湿26次(21%)、攻逐2次(2%),新方分析孙氏核心组合25对,叶氏核心组合12对。结论:二者对水肿核心病机存在不同认识,孙氏认为由五脏失利,水气泛溢,且多由肺起;叶氏认为此证本质上分为肿和胀,治在脾胃;用药规律方面孙氏常用“泻肺逐水”为法,代表药有葶苈子、杏仁、桑白皮、甘遂等,叶氏多用“温阳祛湿”为法,代表药有附子、干姜、桂枝、茯苓、豆蔻等;数据挖掘:推导出新方各11首,为水肿的进一步理解和治疗提供参考。
English Summary:
      Edema patients with lingering conditions,Chinese medicine in the treatment of edema disease has unique advantages,summing up the experience of Chinese medicine in this syndrome has unique clinical significance. Methods:Through the traditional Chinese medicine inheritance auxiliary platform system,this study analyzed and compared the similarities and differences between SUN Simiao and Ye Tianshi in the treatment of edema. Results:There were 86 prescriptions of Sun Simiao edema,including 154 herbs; 91 prescriptions of Ye Tianshi,including 136 herbs,of which the drugs used by Shangsun and Ye were mainly pungent,sweet and bitter herbs,and the four qi attributes:the frequency of cold drugs used was significantly different between the 2,Sun's warm drugs (44%),cold drugs (31%),Ye's warm drugs (48%),and cold drugs (22%); in terms of treatment,Sun's use of Lishui method 61 times (45%),Wenyang method 23 times (17%),Huoxue method 13 times (10%),Qushi method 10 times (7%),attack method 29 times (21%),Ye's use of Lishui method 57 times (46%),Wenyang 35 times (28%),Huoxue 5 times (4%),Qushi 26 times (21%),attack 2 times (2%). Conclusion:There are different understandings of the core of edema between the 2 groups. SUN believes that the five viscera are lost,water and gas overflow,and most of them are from the lung; Ye believes that this syndrome is essentially divided into swelling and distension,which is treated in the spleen and stomach; in terms of medication rules,Sun commonly uses “purging lung and water” as the method,representing drugs such as Qizi,Almond,Morus alba,Gansui,etc.,Ye mostly uses “warming yang and eliminating dampness” as the method,representing drugs such as aconite root,dried ginger,Guizhi,Poria cocos,cardamom,etc.; data mining:11 new prescriptions are derived to provide a reference for further understanding and treatment of edema.
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