自我管理对类风湿性关节炎患者疼痛缓解的效果评价:Meta分析和系统评价
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国家自然科学基金面上项目(81673990);国家自然科学基金优秀青年科学基金项目(81822050);国家教育部创新团队(IRT1270);国家科技部重点领域创新团队(2015RA4002)作者简介:鲍嘉敏(1996.07—),女,硕士研究生,研究方向:慢性筋骨病的中西医结合康复,E-mail:baojiamin0724@163.com


Evaluation of the Effects of Self-Management on Pain Relief in Patients with Rheumatoid Arthritis:A Meta-Analysis and Systematic Reviews
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    目的:分析自我管理对类风湿性关节炎患者疼痛缓解的效果。方法:通过检索PubMed、Embase、Web of Science、Cochrane Library、Clinical Trails 5个数据库1980年1月1日至2018年7月31日的文献,按照纳入标准筛选文献后,收集以自我管理对RA患者疼痛缓解研究的随机对照试验,提取所需数据用RevMan 5.3软件进行Meta分析。结果:共纳入8篇文献,采用Cochrane协作网的“偏倚风险评估”工具对文献质量进行评价,其中6篇文献为A级(低度偏倚),2篇文献为B级(中度偏倚)。Meta分析结果显示,VAS疼痛评分(SMD=-0.32,P=0.50);疼痛自评(SMD=0.10,P=0.65);生命质量评分QoL(SMD=-0.72,P=0.38);健康评估问卷HAQ(MD=-0.12,P=0.31);DAS-28(MD=-0.28,P=0.42。结论:自我管理对RA患者疼痛缓解差异没有统计学意义。其临床及家庭应用价值和意义还需要进一步的证实。

    Abstract:

    To analyze the effects of self-management on pain relief in patients with rheumatoid arthritis.Methods:By searching the 5 databases of PubMed,Embase,Web of Science,Cochrane Library,the literature from January 1,1980 to July 31,2018,after been screened the literature according to the inclusion criteria,a randomized controlled trial of self-management on pain relief studies in RA patients was collected and the required data were extracted for Meta-analysis which using RevMan 5.3software.Results:A total of 8 literature were included.The Cochrane Collaboration's tool for assessing risk of bias was used to evaluate the quality of the literature.Among them 6 of the studies were Grade A(low-biased)and 2 studies were Grade B(moderately biased).Meta-analyzes showed Visual Analogue Scale(VAS,SMD=-0.32,P=0.50),Pain Self-Efficacy(SMD=0.10,P=0.65),quality of life(QoL,SMD=-0.72,P=0.38),Health Assessment Questionnaire(HAQ,MD=-0.12,P=0.31),DAS-28(MD=-0.28,P=0.42).Conclusion:Self-management did not have statistical significance for pain relief difference in RA patients.Its clinical and family application's value and significance still needs further confirmation.

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鲍嘉敏,宋永嘉,陈锦漫,梁倩倩,王拥军.自我管理对类风湿性关节炎患者疼痛缓解的效果评价:Meta分析和系统评价[J].世界中医药,2020,(07).

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  • 收稿日期:2019-02-19
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  • 在线发布日期: 2020-04-27
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