| 引用本文:叶海森1，武凯歌1，张湘斌2，陈曦1，周霞峰1，曹慧1.醒脑开窍针刺法治疗血管性痴呆患者的疗效[J].世界中医药,2020,(07):. |
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| 醒脑开窍针刺法治疗血管性痴呆患者的疗效 |
| Effects in Patients with Vascular Dementia Using Acupuncture Method of Inducing Resuscitation |
| 投稿时间：2020-02-06 |
| DOI：10.3969/j.issn.1673-7202.2020.07.023 |
| 中文关键词: 醒脑开窍针 血管性痴呆 简易智能状态量表 基质金属蛋白酶 |
| English Keywords:Acupuncture method of inducing resuscitation VD Barthel Indexes MMP |
| 基金项目:湖南省自然科学基金项目(2019JJ8002680026) |
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| 中文摘要: |
| 目的：探究醒脑开窍针刺法对血管性痴呆(VD)患者的简易智能状态量表（MMSE）评分、Barthel指数及基质金属蛋白酶（MMP）的影响。方法：选取2017年1月至2018年1月湖南省脑科医院收治的血管性痴呆患者共110例作为研究对象，随机分为观察组和对照组，每组55例。对照组采用常规针刺疗法；观察组采用醒脑开窍针刺疗法，2组疗程均为4周。比较2组患者治疗后治疗有效率及治疗前后MMSE、Barthel指数及MMP水平。结果：观察组、对照组的治疗有效率分别为92.72%和78.18%，差异有统计学意义（P<0.05）；治疗后2组患者MMSE和Barthel指数均显著升高，差异有统计学意义（P<0.05），且观察组高于对照组，差异有统计学意义（P<0.05）；治疗后2组患者的MMP-2和MMP-9值均下降，差异有统计学意义（P<0.05），且观察者组患者的MMP-2和MMP-9低于对照组，差异有统计学意义（P<0.05）。结论：醒脑开窍针刺法对VD患者疗效显著，能够有效缓解痴呆症状。 |
| English Summary: |
| To explore the effects on MMSE scores, Barthel indexes and matrix metalloproteinase (MMP) in patients with vascular dementia (VD) by using acupuncture method of inducing resuscitation.Methods:A total of 110 patients with VD in Hunan Brain Hospital were randomly divided into an observation group (55 cases) and a control group (55 cases).The control group was treated with routine acupuncture method while the observation group was treated with acupuncture method of inducing resuscitation.There were 2 weeks of treatment for the 2 groups.The total effective rates, MMSE scores, Barthel indexes and levels of MMP were compared between the 2 groups.Results:The total effective rates in the observation group and the control group were 92.72 % and 78.18 %, respectively, with significant difference (P<0.05).After treatment, the MMSE scores and Barthel indexes in the 2 groups increased significantly (P<0.05), and those in the observation group were higher than those in the control group, with significant difference (P<0.05).After treatment, the levels of MMP-2 and MMP-9 in the 2 groups decreased significantly (P<0.05); Moreover, those in the observation group were lower than those in the control group, with significant difference (P<0.05).Conclusion:Acupuncture method of inducing resuscitation is an effective therapy in treating VD patients and can effectively relieve the symptoms of dementia, which is worthy for further promotion and application. |
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