This paper analyzes Professor ZHU Kejian's experience in treating liver cancer from 3 aspects:the analysis of the academic thoughts of liver cancer, the summary of clinical experience and the analysis of typical medical records.It is concluded that Professor ZHU Kejian's treatment of liver cancer is based on the accumulation of damp,heat, toxin, and the injury of liver, spleen, qi and blood.The treatment is the method of detoxifying and anticancer, dispersing the stagnated liver-energy and regulating spleen, which can be used for clinical references.