| 引用本文:尹磊淼1,2.表面等离子共振技术在中医药研究中应用进展[J].世界中医药,2020,(11):. |
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| 表面等离子共振技术在中医药研究中应用进展 |
| Clinical Progress of Surface Plasmon Resonance in Traditional Chinese Medicine Study |
| 投稿时间：2020-05-10 |
| DOI：10.3969/j.issn.1673-7202.2020.11.008 |
| 中文关键词: 表面等离子共振 中医药 针灸 靶标 生物传感器 机制研究 |
| English Keywords:Surface plasmon resonance (SPR) Traditional Chinese medicine Acupuncture Target Biosensor Mechanism research |
| 基金项目:国家自然科学基金项目(81922076，81873373)；上海市青年拔尖人才开发计划项目；上海市协同创新建设项目(ZYJKFW201701005，ZYJKFW201811010) |
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| 中文摘要: |
| 利用表面等离子共振现象制备的生物传感技术具有无标记、灵敏度高、通量大、特异性强，样品耗损少等优点，在生命科学等众多学科中得到了广泛的关注和应用。近年来该技术也被运用在不少中医药研究的重要领域。本文简要介绍了表面等离子共振原理，总结并评述了在中医药新靶标发现、优效小分子寻找等方向的研究进展和前景。 |
| English Summary: |
| Biosensor technology based on surface plasmon resonance (SPR) phenomenon has been widely concerned and applied in recent years because of its advantages，such as no labeling，sensitivity，high-throughput，specificity，low sample consumption，etc.In the study of the mechanism of traditional Chinese medicine (TCM)，SPR biosensor technology has also been used in many fields in recent years.In this paper，the principle of SPR is briefly introduced.The research progress and prospect in the fields，including the new target discovery of TCM and searching for small molecules with best performance，are summarized and reviewed. |
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