Hypertension is the leading risk factor for heart attack and stroke, which seriously threatens the physical and mental health of our people. Generally, hypertension has been regarded as a disorder of the regulation of salt-water balance and cardiovascular function systems: regulated by the renin-angiotensin-aldosterone system (RAAS) and the sympathetic nervous system (SNS). However, there are still about 40% of patients in the clinical treatment by restricting the RAAS system or the SNS system to regulate blood pressure, which shows that the pathogenesis mechanisms of hypertension involves in other mechanisms such as immune mechanisms. Modern traditional Chinese medicine research shows that the traditional Chinese medicine has the function of regulating immunity. Traditional Chinese medicine is often used clinically to control hypertension and has good results. This paper summarizes the non-immune and immune mechanisms of hypertension, and explores how traditional Chinese medicine can control blood pressure by regulating the function of the immune system. Therefore, that better explained that when using Chinese medicine to lower blood pressure, it can have better efficacy of hypertension control on the basis of conventional Western medicine, but it is not ideal when applied alone.