| 引用本文:赵雪松1，樊永平1，杨涛1，齐崇2，王思佳2，杨松2，孟蓝熙2.补肾益髓方对复发缓解型多发性硬化患者睡眠及生命质量的影响[J].世界中医药,2020,(12):. |
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| 补肾益髓方对复发缓解型多发性硬化患者睡眠及生命质量的影响 |
| Effects of Bushen Yisui Formula on Sleep and Quality of Life in Patients with Relapsing-remitting Multiple Sclerosis |
| 投稿时间：2019-05-14 |
| DOI：10.3969/j.issn.1673-7202.2020.12.018 |
| 中文关键词: 多发性硬化 复发缓解 生命质量 匹兹堡睡眠质量指数量表 测疲劳量表 |
| English Keywords:Multiple sclerosis Relapsing-remitting Quality of life PSQI Fatigue Scale-14 |
| 基金项目:国家自然科学基金项目(81473640);北京市自然科学基金项目(7142053);北京市中医药科技项目(QN2014-17);首都医科大学附属北京天坛医院青年科研基金项目(2014-YQN-YS-06);北京市中医药科技项目(JJ2018-49);首都医科大学科研培育基金项目(PYZ2018142) |
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| 中文摘要: |
| 目的:研究补肾益髓方对复发缓解型多发性硬化患者生命质量的影响。方法:选取2015年1月至2016年12月首都医科大学附属北京天坛医院收治的复发缓解型多发性硬化患者作为观察组（n＝30）,选取健康志愿者作为对照组（n＝10）,观察组口服补肾益髓方,治疗半年,治疗前后测疲劳量表(Fatigue Scale-14)、匹兹堡睡眠质量指数量表(PSQI)和多发性硬化生命质量问卷(MSQOL-54)。结果:与对照组比较,观察组Fatigue Scale-14得分显著升高(P<0.01),MSQOL-54显著降低(P<0.01),PSQI中的入睡时间得分、睡眠效率得分、睡眠障碍得分、日间障碍得分和总得分显著升高(P<0.05)。与本组治疗前比较,观察组治疗后Fatigue Scale-14降低(P<0.05),MSQOL-54升高(P<0.05),PSQI降低,但差异无统计学意义。结论:复发缓解型多发性硬化患者服用补肾益髓方后,生命质量提高。 |
| English Summary: |
| To study the effects of Bushen Yisui Formula on the quality of life in the patients with relapsing-remitting multiple sclerosis.Methods:A total of 30 patients with relapsing-remitting multiple sclerosis admitted to Beijing Tiantan Hospital，Capital Medical University from January 2015 to December 2016 were selected as the observation group，and 10 healthy patients were selected as the control group.The patients in the control group were treated with Bushen Yisui Formula for half one year，and the Fatigue Scale Table before and after treatment (Fatigue Scale-14)，Pittsburgh Sleep Quality Index (PSQI) and Multiple Sclerosis Quality of Life Questionnaire (MSQOL-54) were measured.Results:Compared with the control group，the Fatigue Scale-14 score was significantly higher in the observation group (P<0.01)，MSQOL-54 was significantly lower (P<0.01)，the sleep time score，sleep efficiency score，sleep disorder score，day disorder score in the PSQI and the total score were significantly increased (P<0.05).Compared with those the before treatment in this group，the Fatigue Scale-14 decreased (P<0.05)，MSQOL-54 increased (P<0.05)，and PSQI decreased，but there was no statistical difference.Conclusion:Patients with relapsing-remitting multiple sclerosis have improved quality of life after taking Bushen Yisui Formula. |
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