To explore the effects of Jinshuibao Tablets combined with enoxaparin on lipid metabolism in patients with maintenance hemodialysis. Methods:A total of 154 patients undergoing dialysis at the Blood Purification Center of Maanshan Shiqiye Hospital between December 2018 and March 2019 were selected as the study objects and were randomly divided into a control group(n=77)and an observation group(n=77). The control group routinely was treated with enoxaparin anticoagulation, and the observation group added Jinshuibao Tablets on the basis of anticoagulation in the control group. The 2 groups were intervened for 3 months to compare the changes in blood lipids and and continuous hemodialysis complications. Results:After the group intervention, the levels of triglyceride, total cholesterol(TC)and low-density lipoprotein cholesterol in the observation group decreased, and high-density lipoprotein cholesterol increased, which were statistically different from those in the control group and before treatment(P<0.05); the total complication rate in the observation group was significantly lower than that in the control group, and the difference was statistically significant(P<0.05); the incidence of adverse reactions of maintenance hemodialysis was lower in the 2 groups, and there was no statistical significant(P>0.05). Conclusion:Jinshuibao Tablet combined with enoxaparin can improve the lipid metabolism level and reduce the complications related to maintenance hemodialysis, which is worthy of clinical application.