| 引用本文:刘梦楠1,2，王敏1,2，白玉莹1,2，徐文娟1,2，李春帅1,2，邹秦文3，李向日1,2，林瑞超1,2.包装对三七粉和熟三七粉稳定性的影响研究[J].世界中医药,2020,(13):. |
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| 包装对三七粉和熟三七粉稳定性的影响研究 |
| Study on the Influence of Packaging on the Stability of Radix Notoginseng Powder and Cooked Radix Notoginseng |
| 投稿时间：2020-06-10 |
| DOI：10.3969/j.issn.1673-7202.2020.13.008 |
| 中文关键词: 三七粉 熟三七粉 加速试验 有效成分 稳定性 |
| English Keywords:Radix Notoginseng Powder Cooked Radix Notoginseng Powder Accelerated test Effective ingredients Stability |
| 基金项目:国家中医药管理局国家中药标准化项目（ZYBZH-Y-YN-44）——三七等2种中药饮片标准化建设 |
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| 中文摘要: |
| 目的:通过考察不同包装下三七粉和熟三七粉外观性状、水分及有效成分含量等变化情况，确定包装对三七粉和熟三七粉稳定性的影响。方法:在恒温恒湿箱中对三七粉和熟三七粉进行加速试验，于0、1、2、3、6月对三七粉和熟三七粉外观性状及含水量进行考察，同时以皂苷类成分的含量作为检测指标，利用本课题组前期建立的高效液相色谱法，对三七粉和熟三七粉中的皂苷类有效成分含量进行检测，并统计分析。结果:所有样品经6个月加速试验后观察未见霉变、虫蛀等现象，外观性状基本一致，水分含量增高但其含量仍符合《中华人民共和国药典》（2015版）规定（水分含量≤14%）。三七粉中人参皂苷Rg1、Rb1、三七皂苷R1含量的总和及熟三七粉中人参皂苷Rk1、Rh4含量的总和无显著减少。真空与非真空2种包装状态对饮片有效成分含量的影响较小，但对饮片的吸湿性有影响。结论:PTE/PE复合而成的食品级铝塑复合膜是较理想的包材，能保证三七粉和熟三七粉质量的稳定，真空包装可以显著降低样品的吸湿程度。 |
| English Summary: |
| To determine the effects of packaging on the stability of Radix Notoginseng powder and cooked Radix Notoginseng powder by investigating the changes of appearance，water content and effective component.Methods:In the constant temperature and humidity box，the accelerated test was carried out on Radix Notoginseng powder and cooked Radix Notoginseng powder.In 0，1，2，3 and 6 months，the appearance character and water content of Radix Notoginseng Powder and cooked Radix Notoginseng Powder were investigated.At the same time，the content of saponins was used as the detection index，and the content of saponins in Radix Notoginseng Decoction pieces was detected and statistically analyzed by the high-performance liquid chromatography established in the earlier stage of our research group.Results:After 6 months of accelerated test，no mildew，moth and other phenomenon were observed in all samples.The appearance of the samples was basically the same.The water content increased，but still met the requirements of Chinese Pharmacopoeia(2015 version)(water content ≤ 14%).The sum of Ginsenoside Rg1，Rb1 and R1 in Radix Notoginseng Powder and the sum of ginsenoside Rk1 and Rh4 in cooked Radix Notoginseng Powder were not significantly reduced.Vacuum and non-vacuum packaging have little effects on the content of effective components，but have a significant effect on the hygroscopicity.Conclusion:The food grade aluminum-plastic composite film made of PTE / PE is an ideal packaging material，which can ensure the stability of the quality of Radix Notoginseng and cooked Radix Notoginseng.Vacuum packaging can significantly reduce the moisture absorption of the sample. |
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