| 引用本文:杨挡1，封亮2,3，刘俊3，赵菁3，李超3，朱法根3，邵建国3，贾晓斌2，孙娥1.基于物料性质表征技术的蒲地蓝消炎口服液儿童用药顺应性改善研究[J].世界中医药,2020,(15):. |
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| 基于物料性质表征技术的蒲地蓝消炎口服液儿童用药顺应性改善研究 |
| Study on Improvement of Children's Medication Compliance of Pudilan Xiaoyan Oral Liquid Based on the Material Property Characterization Technology |
| 投稿时间：2020-07-01 |
| DOI：10.3969/j.issn.1673-7202.2020.15.005 |
| 中文关键词: 物料性质表征技术 复合矫味技术 剂型优化技术 顺应性 精准用药 |
| English Keywords:Material property characterization technology Compound flavoring technology Formulation optimization technology Compliance Precise medication |
| 基金项目:国家重点研发计划项目(2018YFC1706902);中国药科大学双一流建设创新团队项目(CPU2018GY11)——中药制剂再评价再发现再创新关键技术研究 |
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| 中文摘要: |
| 蒲地蓝消炎口服液安全有效,显效迅速,临床应用广泛,但在儿科用药领域,由于用药剂量不明确与口服顺应性差成为制约其发展的主要原因。基于此,本研究通过分析其问题产生的根源并深入探究其解决方案,通过物料性质表征技术、复合矫味技术、剂型优化技术以提升蒲地蓝消炎口服液的口服顺应性,同时探讨蒲地蓝消炎口服液的儿童精准用药策略,为儿童精准用药的临床前研究提供技术指导。 |
| English Summary: |
| Pudilan Xiaoyan Oral Liquid is safe and effective, significantly effective and widely used in clinics.However, in the field of pediatric medicine, unclear dosage and poor oral compliance are the main reasons that restrict its development.Therefore, the study analyzes the root cause of the problem and explores its solution in depth, and improves the oral compliance of Pudilan Xiaoyan Oral Liquid by material property characterization technology, compound flavoring technology and formulation optimization technology.Simultaneously, the precise medication strategy of Pudilan Xiaoyan Oral Liquid for children is explored, which will provide technical guidance for preclinical research on precise medication for children. |
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