Pudilan Xiaoyan Oral Liquid is safe and effective, significantly effective and widely used in clinics.However, in the field of pediatric medicine, unclear dosage and poor oral compliance are the main reasons that restrict its development.Therefore, the study analyzes the root cause of the problem and explores its solution in depth, and improves the oral compliance of Pudilan Xiaoyan Oral Liquid by material property characterization technology, compound flavoring technology and formulation optimization technology.Simultaneously, the precise medication strategy of Pudilan Xiaoyan Oral Liquid for children is explored, which will provide technical guidance for preclinical research on precise medication for children.