To explore the effects of electroacupuncture on the NLRP3 inflammatory body in gouty knee arthritis of damp heat stasis type.Methods:A total of 106 patients with gouty knee arthritis of damp heat stasis type in the Fourth People's Hospital of Panzhihua City were divided into a control group and a study group,with 53 cases in each group.The control group was treated with Western medicine and the study group was treated with electroacupuncture based on the control group for 1 week.The changes of NLRP3 inflammatory body and its protein,inflammatory factors,quality of life,vascular endothelial cells were observed and compared before and after treatment in the 2 groups and the curative effects were summed up.Results:The improvement of Caspase-1,ASC,TNF-α,IL-1 β,CRP,ESR,UA,IL-10,IL-4,ET-1,MPO,sICAM-1 and NO in the observation group were better than those in the control group (P<0.05).The improvement of physiological function,physiological action,body pain,general health and social function in the observation group was higher than that in the control group (P<0.05),and the total clinical effective rate was significantly higher than that in the control group (P<0.05).Conclusion:Electroacupuncture could inhibit the inflammatory body and protein of NLRP3,inhibit the inflammatory reaction,promote the vascular permeability,and improve the quality of life and therapeutic effects. |