世界中医药
文章摘要
引用本文:袁丽莎1,肖永华2,钟剑2,国凤霞2,窦仲萍2,关静3,曹钋2,任可4,李建军5,马迎春6,魏宇2,裴志行1.基于因子分析探索血液透析患者中医证候要素[J].世界中医药,2020,(15):.  
基于因子分析探索血液透析患者中医证候要素
Exploration of TCM Syndrome Elements in Hemodialysis Patients Based on Factor Analysis
投稿时间:2019-07-18  
DOI:10.3969/j.issn.1673-7202.2020.15.026
中文关键词:  慢性肾脏病5期  尿毒症  维持性血液透析  横断面研究  多元统计分析  因子分析  舌象  证候要素  中医证型
English Keywords:Chronic kidney disease stage 5  Uremia  Maintenance hemodialysis  Cross-sectional study  Multivariate statistical analysis  Factor analysis  Tongue image  Syndrome elements  TCM Syndrome type
基金项目:国家重点研发计划中医药现代化研究重点专项(2017YFC1703300)
作者单位
袁丽莎1,肖永华2,钟剑2,国凤霞2,窦仲萍2,关静3,曹钋2,任可4,李建军5,马迎春6,魏宇2,裴志行1 1 北京中医药大学第一临床医学院北京100029 2 北京中医药大学东直门医院肾病内分泌科北京100700 3 北京中医药大学基础医学院北京100029 4 北京中医药大学东方医院肾病科北京100078
5 北京中医药大学东直门医院东区透析室
北京101121 6 中国康复医学研究中心北京博爱医院肾病科北京100068 
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中文摘要:
      目的:研究慢性肾脏病(CKD)5期进行维持性血液透析(MHD)患者的中医证候要素特征。方法:选取2019年1月至2019年5月多中心调查的MHD患者286例作为研究对象,采用流行病学方法,收集一般资料及中医症状信息,同时采用舌象仪采集舌象信息,运用因子分析的方法对症状及舌象数据进行统计分析,在中医理论指导下,综合公因子中医证候含义。结果:共提取12个公因子,病位证素有肾、脾、肝、心、胃,以肾、脾、肝为主,病性证素有气虚、阴虚、阳虚,以气虚、阴虚为主,病邪证素有湿、热、血瘀、风动,以湿、热、血瘀为主。结论:CKD5期MHD患者本虚标实并见,本虚包括脾肾气虚、脾肾阳虚、肝肾阴虚、气阴两虚,实证包括肾络瘀热、肝胆湿热,虚实夹杂包括脾虚湿浊、肾虚湿热、气虚血瘀、阴虚风动。
English Summary:
      To study the characteristics of TCM syndrome elements in patients with maintenance hemodialysis (MHD) during chronic kidney disease stage 5 (CKD5).Methods:By epidemiological methods,a total of 286 MHD patients from a multi-center survey from January 2019 to May 2019 were selected as the research objects to collect general information and TCM symptom information.At the same time,tongue image information was collected by tongue imager.Factor analysis was used to statistically analyze the symptoms and tongue image data.The meaning of the common factor of TCM syndrome was summarized according to the theory of traditional Chinese medicine.Results:A total of 12 common factors were extracted.The disease location elements included the kidney,the spleen,the liver,the heart and the stomach.The kidney,the spleen and the liver were the main factors.The syndrome elements of the disease nature were qi deficiency,yin deficiency and yang deficiency,in which the main factors were the qi deficiency and yin deficiency.The syndrome elements of pathogenic factors were dampness,heat,blood stasis,stiring wind,with dampness,heat,blood stasis as the main elements.Conclusion:MHD patients in CKD5 5 stage was deficient in origin and excessive in superficiality.The origin deficiency includes spleen-kidney qi deficiency,spleen-kidney yang deficiency,liver-kidney yin deficiency and qi-yin deficiency.While excessive superficiality includes kidney collateral blood stasis-heat,dampness-heat of liver and gallbladder,intermingled deficiency and excess includes spleen deficiency due to dampness and turbidity,kidney deficiency due to dampness and heat,blood stasis due to qi deficiency and stirring wind due to yin deficiency.
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