| 引用本文:钟蕊1，翁志军2,3，赵继梦2,3，李昆珊2，吴璐一2，黎梅1，黄艳2,3，顾沐恩2，周志刚4，许琼1.艾灸治疗溃疡性结肠炎效应机制研究进展[J].世界中医药,2020,(15):. |
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| 艾灸治疗溃疡性结肠炎效应机制研究进展 |
| Research Progress on the Mechanism of Moxibustion in the Treatment of Ulcerative Colitis |
| 投稿时间：2020-05-14 |
| DOI：10.3969/j.issn.1673-7202.2020.15.031 |
| 中文关键词: 溃疡性结肠炎 艾灸 肠黏膜屏障 细胞凋亡 免疫平衡 |
| English Keywords:Ulcerative colitis Moxibustion Intestinal mucosal barrier Apoptosis Immune balance |
| 基金项目:国家自然科学基金面上项目（81674074）——基于VDR信号通路探讨艾灸对UC肠道抗菌肽的调控机制研究；上海市卫生计生委优秀人才培养计划项目(2018YQ11)——艾灸干预溃疡性结肠炎E3泛素连接酶TRIM31的免疫调节机制；上海市扬帆计划(17YF1417600)——针灸调控UC结肠组织差异表达circRNAs筛选与生物信息学挖掘 |
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| 中文摘要: |
| 检索2010年1月至2020年2月万方数据库（Wangfang Data）、中国期刊全文数据库（CNKI）、维普中文期刊平台（VIP）及Pubmed数据库中，艾灸治疗溃疡性结肠炎（Ulcerative Colitis，UC）临床与实验机制研究文献。以“艾灸”或“灸法”或“moxibustion”“溃疡性结肠炎”或“炎症性肠病”或“ulcerative colitis”为检索词，纳入临床或实验机制研究文献，排除综述类文献、个案、病例报告等，最终筛选出46篇国内外相关文献，以此总结近10年艾灸治疗UC临床及实验机制。从调节患者免疫平衡、调节肠道菌群、改善肠黏膜屏障功能、调节细胞凋亡进行分析综述并对未来研究提出思考与展望。 |
| English Summary: |
| The author searched clinical and experimental mechanism literatures of moxibustion treatment of ulcerative colitis(UC)in Wangfang Data，China Journal Full-text Database(CNKI)，VIP Chinese Journal Platform(VIP)and Pubmed Database from January 2010 to February 2020.“艾灸” or “灸法” or “moxibustion”，“ulcerative colitis” or “inflammatory bowel disease” or “ulcerative colitis” were used as search terms to include clinical or experimental mechanism research literature.Review literatures，cases，case reports etc.，were excluded.Finally 46 domestic and foreign related literatures were selected to summarize the clinical and experimental mechanisms of moxibustion treatment of UC in the past ten years.The author analyzed and reviewed the immune balance of the patients，regulation of intestinal flora，improvement of intestinal mucosal barrier function，and apoptosis regulationes of，and proposed the thinking and prospects for future research. |
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