| 引用本文:王维1，李志红1，姜尚上1，于琦2，丁霞1，常炳龙1，康雷1，赵晓东1.基于古今医案云平台的名医秦伯未膏方用药规律研究[J].世界中医药,2020,(16):. |
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| 基于古今医案云平台的名医秦伯未膏方用药规律研究 |
| Study on the Medication Rules of Qin Bowei's Ointment Formula Based on Ancient and Modern Medical Cases Cloud Platform |
| 投稿时间：2019-12-09 |
| DOI：10.3969/j.issn.1673-7202.2020.16.031 |
| 中文关键词: 名医秦伯未 膏方 用药规律 数据挖掘 古今医案云平台 |
| English Keywords:The famous doctor Qin Bowei Ointment formula Medication rules Data mining Ancient and modern medical cases cloud platform |
| 基金项目:国家重点研发计划（2018YFC1704100）——基于‘道术结合’思路与多元融合方法的名老中医经验传承创新研究”；名老中医经验研究与推广应用一体化平台构建（2018YFC1704106） |
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| 中文摘要: |
| 目的：基于古今医案云平台(V2.1)，分析名医秦伯未膏方的用药规律，为临床研究秦老膏方用药规律及传承其学术思想提供指导。方法：收集《秦伯未医案》《膏方大全》《谦斋膏方案》及《秦伯未先生膏方选集》中所载秦老膏方，录入古今医案云平台(V2.1)，采用软件集成的数据分析功能分析其膏方用药规律。结果：通过对书中所载238首方剂进行分析，筛选得到的369味药物中用药频数在90次以上的共17味，药物关联分析显示置信度较高的药物组合包括“砂仁—熟地黄”“党参，枸杞子—熟地黄”“枸杞子—熟地黄”“山萸肉—熟地黄”等。药物属性、功效统计显示药物性味以温性、平性、甘味、苦味、辛味为主，归经以归肾、肝、肺经为主，功效以补肝肾为主，聚类分析显示高频药物具体可分为4种不同功用的组合，复杂网络分析显示核心处方为归肾丸合归脾丸加减。结论：通过对《秦伯未医案》《膏方大全》《谦斋膏方案》及《秦伯未先生膏方选集》中所载秦老膏方进行数据分析，以期指导临床运用膏方及传承秦老膏方用药经验和学术思想。 |
| English Summary: |
| Based on the Ancient and Modern Medical Cases Cloud Platform (V2.1), analyze the medication rules of the famous doctor Qin Bowei's ointment formula, and provide guidance for clinical researches of Qin's ointment formula medication rules and his academic thoughts. Methods:Qin's ointment formula contained in “Qin Bowei's Medical Cases”, “Encyclopedia of Ointment Formula”, “Collection of Qian Zhai's Ointment Formula” and “Selections of Qin Bowei's Ointment Formula” were collected and record in the Ancient and Modern Medical Cases Cloud Platform (V2.1). The medication rule of his ointment formula was analyzed by the software. Results:Through the analysis of 238 prescriptions contained in the book, a total of 17 herbs with a frequency of use for more than 90 times were screened out from the 369 herbs. The drug association analysis showed that the drug combination with higher confidence included “villous amomum fruit-prepared rehmannia root”“tangshen, barbary wolfberry fruit-prepared rehmannia root”“asiatic cornelian cherry fruit-prepared rehmannia root” and so on. The statistics of drug properties and efficacy showed that the character of herb is mainly warm,neutral, sweet, bitter, and spicy, and the channel entry are mainly kidney, liver, and lung, and the efficacy is mainly based on reinforcing liver and kidney. Cluster analysis showed that high-frequency drugs can be specifically divided into four different combinations of functions, and complexed network analysis showed that the core prescription is Guishen Pills and Guipi Pills. Conclusion:Through the data analysis of “Qin Bowei's Medical Cases”, “Encyclopedia of Ointment Formula”, “Collection of Qian Zhai's Ointment Formula” and “Selections of Qin Bowei's Ointment Formula”， the data can be used to guide clinical application and to inherit the medication experience and academic thought of Qin's ointment formula. |
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