世界中医药
文章摘要
引用本文:嵇玉华1,吴红波2.调中饮对功能性消化不良患儿胃肠激素和胃电图的影响[J].世界中医药,2020,(17):.  
调中饮对功能性消化不良患儿胃肠激素和胃电图的影响
Effects of Tiaozhong Drink on Gastrointestinal Hormones and Electrogastrogram in Children with Functional Dyspepsia
投稿时间:2020-06-25  
DOI:10.3969/j.issn.1673-7202.2020.17.019
中文关键词:  功能性消化不良  调中饮  胃肠激素  胃电图
English Keywords:Functional dyspepsia  Tiaozhong Drink  Gastrointestinal hormone  Electrogastrogram
基金项目:山东省中医药科技发展计划项目(2017-006)
作者单位
嵇玉华1,吴红波2 1 山东省烟台市烟台山医院儿童保健科烟台264001 2 山东省济南市第二妇幼保健院儿童保健科济南271100 
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中文摘要:
      目的:探讨调中饮对功能性消化不良(FD)患儿胃肠激素和胃电图的影响。方法:选取2014年8月至2017年8月烟台市烟台山医院收治的FD患儿123例作为研究对象,按照随机数字表法随机分为对照组(n=61)与观察组(n=62)。对照组进行常规治疗,观察组在对照组基础上采用调中饮治疗,2组均连续治疗1个月。比较2组临床疗效及主要中医症状积分;比较2组治疗前后胃肠激素及胃电图变化。结果:治疗后观察组总有效率(85.48%)显著高于对照组(72.13%)(P<0.01)。与治疗前比较,治疗后2组患儿腹胀、上腹灼热、腹痛、嗳气、恶心呕吐等症状积分及血清SS含量均显著降低,且观察组低于对照组(P<0.05或P<0.01);而血清MLT、GAS、SP含量显著升高,且观察组MLT与SP含量高于对照组(P<0.05或P<0.01);与治疗前比较,治疗后2组患儿FP、正常慢波比率水平及正常胃电节律患儿比例均显著升高,且观察组高于对照组(P<0.05或P<0.01);而胃电节律过缓患儿比例显著下降,且观察组低于对照组(P<0.05或P<0.01)。结论:调中饮治疗儿童FD可显著缓解患儿临床症状,促进胃肠激素水平恢复正常,同时可有效改善胃电图,临床疗效良好。
English Summary:
      To study the effects of Tiaozhong Drink on gastrointestinal hormone and electrogastrogram in functional dyspepsia(FD)children.Methods:A total of 123 FD child patients admitted to Yantai Mountain Hospital of Yantai were selected as the research objects and randomly divided into an observation group(n=62)and a control group(n=61).The control group was given conventional chemotherapy,and the observation group was treated with Tiaozhong Drink for on the basic of control group.Both 2 groups were treated continuously for 1 month.The clinical efficacy and scores of main TCM symptoms in 2 groups of child patients were compared; the gastrointestinal hormones and electrogastrogram changes before and after treatment in 2 groups were also compared.Results:After treatment,the total effective rate of the observation group(85.48%)was significantly higher than that of the control group(72.13%)(P<0.01).Compared with those before treatment,the symptoms scores of abdominal distention,abdominal scorching hot,abdominal pain,belching,nausea and vomiting and serum content decreased significantly in 2 groups after treatment,and observation group was significantly lower than control group(P<0.05 or P<0.01); and the serum MLT,GAS and SP content increased significantly and the MLT and SP contents in observation group were significantly higher than those in control group(P<0.05 or P<0.01); compared with those before treatment,the levels of FP,normal slow wave ratio and the proportion of child patients with normal gastric electrical rhythm in 2 groups after treatment increased significantly,and observation group was significantly higher than the control group(P<0.05 or P<0.01); and the proportion of children with slow gastric rhythm decreased significantly,and observation group was significantly lower than the control group(P<0.01).Conclusion:Tiaozhong Drink in the treatment of children with FD can significantly relieve the clinical symptoms of child patients,promote the recovery of gastrointestinal hormone levels,and effectively improve the electrogastrogram,with good clinical effects.
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