| 引用本文:梁忠喆1，李道成2，张亚文1，黄嘉欣1.电针辅助中药治疗子宫内膜异位症对肿瘤标志物水平的影响[J].世界中医药,2020,(17):. |
|
| 电针辅助中药治疗子宫内膜异位症对肿瘤标志物水平的影响 |
| Effects of Electroacupuncture Assisted Traditional Chinese Medicine on the Level of Tumor Markers for the Treatment of Endometriosis |
| 投稿时间：2020-06-25 |
| DOI：10.3969/j.issn.1673-7202.2020.17.025 |
| 中文关键词: 子宫内膜异位症 电针 补肾祛瘀方 肿瘤标志物 疗效 |
| English Keywords:Endometriosis Electroacupuncture Bushen Quyu Formula Tumor markers Curative effects |
| 基金项目:广东省中医药局科研项目（20194005） |
|
| 摘要点击次数: 389 |
| 全文下载次数: 0 |
| 中文摘要: |
| 目的：探讨电针辅助中药治疗子宫内膜异位症（EMS）及对患者肿瘤标志物水平的影响。方法：选取2016年4月至2017年5月广州中医药大学第一附属医院收治的EMS患者150例作为研究对象，按照随机数字表法随机分为对照组和观察组，每组75例，对照组给予曲唑片+地屈孕酮片治疗，观察组在对照组的基础上联合电针及补肾祛瘀方治疗，连续治疗6个月。观察2组临床疗效及随访期间复发情况，治疗前后检测并比较2组血清肿瘤标志物及激素水平变化。结果：治疗后观察组临床治疗总有效率为89.33%，较对照组的76.00%显著升高（P<0.05）。随访期间观察组和对照组分别有10、25例复发，复发率分别为13.33%、33.33%，观察组复发率低于对照组（P<0.01）。治疗后2组血清CA125、CA19-9含量及阳性率均降低（P<0.01），且观察组低于对照组（P<0.01）；2组血清LH、E2、P、FSH、PGE2水平较治疗前降低，6-k-PGF1α水平较治疗前升高，且2组间差异有统计学意义（P<0.05或P<0.01）。结论：电针辅助中药治疗EMS可显著降低肿瘤标志物水平，调控激素水平，且复发率低，临床疗效确切。 |
| English Summary: |
| To explore the effects of electroacupuncture assisting traditional Chinese medicine on endometriosis(EMS)and the level of tumor markers in patients.Methods:A total of 150 patients admitted to the First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine from April 2016 to May 2017 were selected as the research objects and were randomly divided into a control group(n＝75)and an observation group(n＝75)according to the random number table method.The control group was treated with trazole tablets plus dydrogesterone tablets，and the observation group was treated with electroacupuncture combined with Bushen Quyu formula on the basis of the control group.The treatment lasted for 6 months.The clinical efficacy and recurrence situation during the follow-up period of the 2 groups were observed.The changes of serum tumor markers and hormone levels were compared between the 2 groups before and after treatment.Results:The total effective rate of the treatment group after treatment was 89.33%，which was significantly higher than 76.00% of the control group(P<0.05).During the follow-up period，10 cases and 25 cases recurred respectively in the observation group and the control group，and the recurrence rates were 13.33% and 33.33% respectively，and the recurrence rate in the observation group was lower than that in the control group(P<0.01).The content and positive rate of serum CA125 and CA19-9 in the 2 groups after treatment decreased(P<0.01)，and the observation group was lower than the control group(P<0.01).After treatment，the levels of serum LH，E2，P，FSH and PGE2 in the 2 groups were significantly lower than that before treatment，the level of serum 6-k-PG F1α was significantly higher than that before treatment，the difference was significant in the 2 groups(P<0.05 or P<0.01).Conclusion:Electroacupuncture assisting Chinese medicine in the treatment of EMS can significantly reduce the levels of tumor markers，regulate the levels of hormone.The recurrence rate is low，and the clinical curative effect is exact. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
