| 引用本文:王菲，张杭洲，朱岩洁，侯留法.益脾理肠汤内服联合中药保留灌肠对慢性结肠炎患者的治疗效果分析[J].世界中医药,2020,(18):. |
|
| 益脾理肠汤内服联合中药保留灌肠对慢性结肠炎患者的治疗效果分析 |
| Analysis of Therapeutic Effect of Yipi Lichang Decoction Combined with Traditional Chinese Medicine Retention Enema on Patients with Chronic Colitis |
| 投稿时间：2019-02-23 |
| DOI：10.3969/j.issn.1673-7202.2020.18.012 |
| 中文关键词: 结肠炎 慢性 益脾理肠汤 中药保留灌肠 外周血 炎性反应 肠道屏障功能 疗效 |
| English Keywords:Colitis Chronic Yipi Lichang decoction Traditional Chinese medicine retention enema Peripheral blood Inflammatory reaction Intestinal barrier function Curative effect |
| 基金项目:河南省医学教育研究项目(Wjlx20150785) |
|
| 摘要点击次数: 288 |
| 全文下载次数: 0 |
| 中文摘要: |
| 目的:探讨益脾理肠汤内服联合中药保留灌肠对慢性结肠炎患者的治疗效果。方法:选取2016年12月至2018年1月河南省中医药研究院附属医院收治的慢性结肠炎患者134例作为研究对象,按照随机数字表法随机分为对照组和观察组,每组67例。对照组患者在常规治疗基础上加入中药保留灌肠治疗,观察组患者在常规治疗基础上加入益脾理肠汤内服联合中药保留灌肠治疗,持续2个疗程。比较2组患者治疗2个疗程后的疗效及血清学指标含量差异。结果:治疗2个疗程后,观察组患者的治疗有效率高于对照组;血清中炎性反应因子C反应蛋白(CRP)、肿瘤坏死因子α(TNF-α)、白细胞介素-6(IL-6)的含量低于对照组;血清中肠道屏障功能指标D-乳酸(D-Lactate)、二胺氧化酶(DAO)、内毒素(Esotoxin)的含量低于对照组(P<0.05)。结论:慢性结肠炎患者在中药保留灌肠同时接受益脾理肠汤内服治疗,可进一步提升治疗效果并减轻机体全身炎性反应、保护肠道屏障功能。 |
| English Summary: |
| To explore the therapeutic effect of Yipi Lichang decoction combined with traditional Chinese medicine retention enema on patients with chronic colitis.Methods:A total of 134 patients of chronic colitis patients visited The Affiliated Hospital of Henan Academy of Chinese Medicine from December 2016 to January 2018 were selected and divided into control group(n=67) and observation group(n=67).Patients in control group were treated with traditional Chinese medicine retention enema on the basis of routine treatment,patients in observation group were treated with Yipi Lichang Decoction plus traditional Chinese medicine retention enema on the basis of routine treatment,2 courses of treatment were given in the 2 groups.The curative effect and serological indexes difference between two groups after 2 courses of treatment were compared.Results:After 2 courses of treatment,effective rate in observation group was higher than that in control group,and the serum levels of inflammatory factors such as CRP,TNF-α,IL-6 were lower than those in control group; serum intestinal barrier function indexes such as D-Lactate,DAO and esotoxin were lower than those in control group(P<0.05).Conclusion:Treatment of chronic colitis patients with traditional Chinese retention enema and Yipi Lichang Decoction can further improve the therapeutic effect,reduce the body's systemic inflammatory response and protect the intestinal barrier function. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
