To compare the clinical efficacy and safety of Biantong Capsules and Maren Runchang Pills in the treatment of constipation after thoracoscopic surgery.Methods:A total of 192 patients undergoing thoracoscopic surgery admitted in Thoracic Surgery，ShenZhen People's Hospital and Clinical Medical College of Jinan University from March 2018 to March 2019 were selected as the research objects，and were divided into a control group and an observation group according to random number method，with 96 cases in each group.The control group was given oral Maren Runchang Capsules，and the observation group was orally administered with Tongbian Capsules.The changes of clinical indicators and immune function levels between the 2 groups were compared.Results:The incidence of constipation and the level of chest pressure in the observation group at 72 h after the operation were significantly differentfrom those in the control group(P<0.05).The overall chest pressure recovery status of the observation group was better than that of the control group; but the average value of time，hospital stay and first defecation time were significantly shorter in the observation group than those in the control group(P<0.05).Changes in immune function levels，postoperative complications and adverse reactions in the 2 groups were better than those in the control group，and the differences between the groups were statistically significant(P<0.05).Conclusion:Biantong Capsules has significant therapeutic effects on constipation after thoracoscopic surgery.The curative effects are better than that of Maren Runchang Pills.It can shorten the hospitalization time of postoperative patients，accelerate the recovery of patients，and regulate the immune function，with less clinical adverse reactions and high security.And it is worthy of clinical application.