| 引用本文:徐超1,2，周青3.基于肠道炎-癌转化早期事件，探讨中医药干预着眼点[J].世界中医药,2020,(18):. |
|
| 基于肠道炎-癌转化早期事件，探讨中医药干预着眼点 |
| Discussion on the Focus of Traditional Chinese Medicine Intervention Based on the Transformation of Early Intestinal Inflammation into Cancer |
| 投稿时间：2019-02-25 |
| DOI：10.3969/j.issn.1673-7202.2020.18.030 |
| 中文关键词: 大肠腺瘤 癌前病变 肠道炎性反应 恶性肿瘤 非可控性炎性反应 防控防治 中药干预 中医体质学 |
| English Keywords:Colorectal adenoma Precancerous lesions Intestinal inflammation Malignant tumor Uncontrollable inflammation Prevention and control Intervention of traditional Chinese Medicine Constitution of traditional Chinese Medicine |
| 基金项目:国家自然科学基金项目（81573978）；国家中医药管理局中医药标准化项目[SATCM-2015-BZ(322)] |
|
| 摘要点击次数: 405 |
| 全文下载次数: 0 |
| 中文摘要: |
| 中医体质学作为一门介于中医基础和中医临床之间的新兴学科。中医未病先防实质上就是通过纠正、改善体质，实施疾病三级预防。大肠癌作为目前威胁人类健康的常见恶性肿瘤之一，发病率逐年上升。在减少大肠癌死亡的因素中，大肠癌癌前病变（大肠腺瘤）的早期诊治、综合预防，显得尤为重要。肠道腺瘤局部炎性反应微环境与肠道恶性肿瘤的发生密切相关。将中医体质学说与中医治未病有效结合是中医预防大肠炎-瘤转变、腺瘤癌变的切入点和有效手段，将为大肠腺瘤的进一步防控提供理论依据。因此，以中医学整体观念为依据，利用系统生物学所具有的整体研究思路来开展中医体质学的研究，将中医治未病、中医体质学说与现代基础实验研究成果有机的结合，建立融中医基础理论、现代生化检测、现代遗传免疫研究、肠道微生态于一体的现代技术平台，实现由未病先防向临床转化应用，为中医药防控炎-瘤转变提供技术示范。 |
| English Summary: |
| Physical Constitution of Traditional Chinese Medicine(TCM)is a new subject between the TCM basics and TCM clinics.In essence，the prevention of disease without illness in TCM is to implement three-level prevention of disease by correcting and improving constitution.colorectal cancer is one of the most common malignant tumors threatening human health.The incidence of colorectal cancer is increasing year by year.Early diagnosis，comprehensive prevention of colorectal precancerous lesions(colorectal adenomas)are particularly important in reducing the mortality of colorectal cancer.Local inflammatory microenvironment of intestinal adenoma is closely related to the occurrence of intestinal malignant tumors.Effective combination of TCM constitution theory and preventive treatment of diseases is the entry point and effective means of preventing Intestinal inflammation-tumor transformation in TCM，which will provide theoretical basis for further prevention and control of colorectal adenoma.Therefore，based on the holistic concept of TCM，the research of TCM constitution is carried out by using the holistic research thinking of system biology.Combining TCM treatment of disease，TCM constitution theory and modern basic experimental research results，we establish a modern technology platform that integrates TCM basic theories，modern biochemical testing，modern genetic immune research，and intestinal microecology，and realize the application of disease prevention to clinical transformation，providing a technical demonstration for the prevention and control of inflammation-tumor transformation in traditional Chinese medicine. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
