To analyze and excavate the prescription law of WanShi FuRenKe in the treatment of postpartum disease by using TCM inheritance assistant platform.Methods:By collecting prescriptions of WanShi FuRenKe to treat postpartum,55 prescriptions were input into TCM inheritance auxiliary platform (V2.5).The data of medication rule was mined by his integrated rule analysis,improved mutual information method,complex system entropy clustering,unsupervised entropy hierarchical clustering data analysis and other methods to analyze and mine the drug use experience of WanQuan in the treatment postpartum diseases in the Ming Dynasty.Results:According to the data analysis of 55 prescriptions,Radix Glycyrrhizae,Radix Angelicae and Radix Ginseng were the most frequently used herbs.The top 3 herbs combinations were Radix Ginseng and Radix Glycyrrhizae; Rhizoma Zingiberis Recens and Radix Glycyrrhizae,Radix Glycyrrhizae and Radix Angelicae.A total of 3 new prescriptions for postpartum disease were extracted:Polen Typhae,Flos Carthami,Radix Ginseng,Cortex Moutan Radicis and Fructus Psoraleae; Rhizoma Ligustici Chuanxiong,Rhizoma Cyperi,Rhizoma Corydalis,Cortex Moutan Radicis,Fructus Psoraleae; Radix Glycyrrhizae,Pericarpium Citri Reticulatae,Rhizoma Zingiberis,Cortex Moutan Radicis,Fructus Psoraleae.Conclusion:WanQuan takes nourishing qi and blood as the main treatment method for postpartum diseases,adding and subtracting treatment according to different syndromes.Meanwhile,the compatibility of drugs is smooth and mild.