世界中医药
文章摘要
引用本文:李恒震1,王帅2,蔡新生1,高建喆1.以参芪为主扶正方治疗恶性肿瘤患者疗效的Meta分析[J].世界中医药,2021,(05):.  
以参芪为主扶正方治疗恶性肿瘤患者疗效的Meta分析
Therapeutic Effect of Fuzheng Formula Mainly Containing Shenqi on Malignant Tumor:A Meta-analysis
投稿时间:2020-04-13  
DOI:10.3969/j.issn.1673-7202.2021.05.020
中文关键词:  扶正  黄芪  人参  恶性肿瘤  免疫功能  生命质量  中医  化疗  Meta分析
English Keywords:Fuzheng  Radix Astragali seu Hedysari  Radix Astragali seu Hedysari  Malignant tumor  Immunologic function  Quality of life  Traditional Chinese medicine  Chemotherapy  Meta analysis
基金项目:山东省卫生厅基金山东省医药科技发展计划项目(2018WS068)
作者单位
李恒震1,王帅2,蔡新生1,高建喆1 1 山东中医药大学济南250355 2 山东省潍坊市中医院潍坊261000 
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中文摘要:
      目的:评估以参芪为主的扶正方及中成药配合化疗药物治疗恶性肿瘤的疗效。方法:通过计算机检索国家知识基础设施数据库(简称中国知网,China National Knowledge Infrastructure,CNKI)、中文科技期刊数据库(简称维普资讯,Chinese Citation Database,CCD)、中国学术期刊数据库(简称万方数据库,China Science Periodical Database,CSPD)等国内数据库以及PubMed、OVID、EmBase等国外数据库,查找有关以参芪为主的扶正方治疗恶性肿瘤的随机对照试验的中英文文献,检索时间为2015年10月到2020年3月。使用RevMan5.3软件对挑选出的文献提取相关数据,针对扶正方的疗效进行数据分析,比较观察组与对照组差异。结果:纳入18篇文献,共计1 724例患者,结果显示观察组疗效优于对照组(RR=1.46,95%CI:1.35~1.59,P<0.000 01)。结论:以参芪为主的扶正方配合化疗治疗恶性肿瘤能够抑制肿瘤生长、增强免疫功能、提高生命质量、减少不良反应发生率。
English Summary:
      To evaluate the efficacy of ShenQi Fuzheng Formula and Chinese patent medicine combined with chemotherapy drugs in the treatment of malignance cancer.Methods:Through computer search of domestic databases such as CNKI,VIP database,Wanfang database and foreign databases such as PubMed,OVID,EmBase,etc.,we searched for Chinese and English literature on randomized controlled trials of Shenqi-based Fuzheng Formula in the treatment of malignant tumors.The retrieval time was nearly 5 years.RevMan5.3 software was used to extract relevant data from selected documents,to analyze the efficacy of Fuzheng Formula,and to compare the differences between the test group and the control group.Results:A total of 18 papers were included,totaling 1 724 patients.The results showed that the test group was superior to the control group in the whole course of treatment of malignant tumors [RR=1.46,95%CI(1.35~1.59),P<0.000 01].Conclusion:ShenQi Fuzheng Formula combined with chemotherapy in the treatment of malignant tumors can inhibit tumor growth,enhance immune function,improve quality of life and reduce the incidence of adverse reactions.The application of this method can effectively treat malignant tumors.
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