| 引用本文:车文文1，杨静雯1，夏小军2，姜小燕2，王平3，潘战宇3，王斌3，王丹1，吕中茜1,4,5，潘兴芳4,5，陈泽林4,5，郭永明1,4,5，史丽萍6，陈波1,4,5，郭义1,5,6.针灸防治癌因性疲乏临床实践指南研究[J].世界中医药,2021,(10):. |
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| 针灸防治癌因性疲乏临床实践指南研究 |
| Study on Clinical Practice Application Guidelines of Acupuncture and Moxibustion in Prevention and Treatment of Cancer-related Fatigue |
| 投稿时间：2021-01-01 |
| DOI：10.3969/j.issn.1673-7202.2021.10.019 |
| 中文关键词: 针灸 艾灸 穴位按压 癌因性疲乏 临床实践指南 临床方案 证据整合与推荐 |
| English Keywords:Acupuncture Moxibustion Acupressure Cancer-related fatigue Clinical practice guidelines Clinical protocol Evidence integration and recommendation |
| 基金项目:国家重点研发计划项目（2019YFC1712200，2019YFC1712204）；2020年度中医药标准化项目（GZT-FJS-2020-202）——标准化人才培养模式的构建及实施应用研究；中国科技协会第五届中国科协青年人才托举工程项目（2019-2021ZGZJXH-QNRC001） |
| 作者 | 单位 | | 车文文1，杨静雯1，夏小军2，姜小燕2，王平3，潘战宇3，王斌3，王丹1，吕中茜1,4,5，潘兴芳4,5，陈泽林4,5，郭永明1,4,5，史丽萍6，陈波1,4,5，郭义1,5,6 | 1 天津中医药大学实验针灸学研究中心，天津，301617； 2 甘肃省肿瘤医院乳腺科，兰州，730050； 3 天津医科大学肿瘤医院国家肿瘤临床医学研究中心，天津，300060； 4 天津中医药大学针灸推拿学院，天津，301617； 5 天津中医药大学国家中医针灸临床医学研究中心，天津，301617； 6 天津中医药大学中医学院，天津，301617 |
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| 中文摘要: |
| 目的：探索针灸防治癌因性疲乏的临床应用方案，为制定临床实践指南提供依据。方法：通过计算机检索国家知识基础设施数据库（CNKI）、中国学术期刊数据库（CSPD）、中文科技期刊数据库（CCD）、中国生物文献、PubMed、EMBASE、Cochrane Library等数据库，全面收集针灸疗法治疗癌因性疲乏的现代文献证据；通过人工检索49本古代医籍，收集关于针灸疗法治疗疲乏的古代文献证据；通过制定发放《针灸干预癌因性疲乏调查问卷》，收集针灸干预癌因性疲乏的现代一线专家经验。整合3方面证据形成针灸防治癌因性疲乏临床推荐方案。结果：现代文献共检索到225篇，其中中文文献141篇，英文文献84篇，经筛选，最终纳入14篇现代文献；古代医籍文献与之相关的条目共10项；临床专家问卷共收回52份。综合3方面研究结果发现针灸治疗癌因性疲乏常用针刺、艾灸、穴位按压、电针、经皮穴位电刺激等疗法；常用穴位为足三里、三阴交、关元、气海、太溪、合谷、中脘、百会、太冲、印堂、天枢。结论：综合3方面证据，形成针灸防治癌因性疲乏的临床推荐应用方案，强烈推荐使用针刺、艾灸、穴位按压等疗法；弱推荐使用经皮穴位电刺激、电针等疗法；推荐使用穴位为足三里、三阴交、关元、气海、太溪、合谷、中脘、内关、百会、太冲、印堂、天枢、神门等穴。 |
| English Summary: |
| To explore the clinical application of acupuncture in the prevention and treatment of cancer-related fatigue，and to provide the basis for the development of clinical practice guidelines.Methods:We searched China national knowledge infrastructure(CNKI)，China Science Periodical Database(CSPD)，Chinese Citation Database(CCD)，Chinese Biological Literature，PubMed，EMBASE and Cochrane Library and other databases to comprehensively collect the modern literature evidence of acupuncture treatment of cancer-related fatigue; collected the ancient literature evidence of acupuncture treatment of cancer-related fatigue by manually searching 49 ancient medical books; collected the modern medical experts' experience of acupuncture intervention of cancer-related fatigue by formulating and distributing the Questionnaire of Acupuncture Intervention On Cancer-Related Fatigue.The 3 aspects of evidence were integrated to form the clinical recommended scheme of acupuncture in the prevention and treatment of cancer-related fatigue.Results:A total of 225 modern literature were retrieved，including 141 Chinese literature and 84 English literature.After sorting out the literature，14 modern literature were finally included; there were 10 items related to ancient medical literature; 52 clinical experts questionnaires were collected.After comprehensive 3 aspects of research results，it was found that acupuncture treatment of cancer-related fatigue commonly used acupuncture，moxibustion，acupoint pressing，electro acupuncture，transcutaneous acupoint electrical stimulation and other therapies; the commonly used acupoints were Zusanli(S36)，Sanyinjiao(SP6)，Guanyuan(CV4)，Qihai(CV6)，Taixi(K3)，Hegu(L14)，Zhongwan(CV12)，Baihui(GV20)，Taichong(LR3)，Yintang(EX-HN3)，Tianshu(S25).Conclusion:Based on the evidence of the 3 aspects，the recommended clinical application scheme of acupuncture for cancer-related fatigue prevention and treatment is formed.Acupuncture，moxibustion and acupoint pressing are strongly recommended; transcutaneous acupoint electrical stimulation and electroacupuncture are weakly recommended; Zusanli(S36)，Sanyinjiao(SP6)，Guanyuan(CV4)，Qihai(CV6)，Taixi(K3)，Hegu(L14)，Zhongwan(CV12)，Neiguan(P6)，Baihui(GV20)，Taichong(LR3)，Yintang(EX-HN3)，Tianshu(S25)，and Shenmen(TF4)etc.are recommended. |
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