| 引用本文:孙敦坡1，姜明孝1，马小闵1，王益松1，刘兆飞1，高绪柱2.大艾段温针灸法治疗肾虚肝郁型弱精症的临床效果[J].世界中医药,2021,(10):. |
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| 大艾段温针灸法治疗肾虚肝郁型弱精症的临床效果 |
| Clinical Observation on the Treatment of Asthenospermia of Kidney Deficiency and Liver Depression Type by Da'aiduan Warming Needle Moxibustion |
| 投稿时间：2020-04-26 |
| DOI：10.3969/j.issn.1673-7202.2021.10.020 |
| 中文关键词: 温针灸 弱精症 肾虚肝郁 精液常规 精浆生化 作用机制 饱和灸量 临床观察 |
| English Keywords:Warm needling moxibuston Asthenospermia Kidney deficiency and liver depression Semen conventional indexes Seminal plasma biochemistry Mechanism of action Saturated moxibustion volume Clinical observation |
| 基金项目:国家临床重点专科建设基金项目（苏中医综[2014]3号，苏财社[2014]5号）；连云港市卫生健康委员会青年基金项目（QN1805）；南京医科大学江苏康达医药卫生发展研究院科研项目（2017NJMUKD024）;南京医科大学康达学院科研发展基金项目（KD2020KYJJYB027） |
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| 中文摘要: |
| 目的:探讨大艾段温针灸法治疗肾虚肝郁型弱精症的临床疗效。方法：选取2018年1月至2019年12月课题病例招募组的肾虚肝郁型弱精症患者140例作为研究对象，按照随机数字表法随机分为观察组，药物对照组，常规温针对照组和普通针刺对照组，每组35例。观察组使用4 cm大艾段进行温针灸，药物组服用硫酸锌片、维生素E软胶囊、五子衍宗丸，常规温针组选用2.5 cm艾段，普通针刺组常规针刺，不加灸。各组均4周为1个疗程，2个疗程后分析4组中医证候、精液常规、精浆生化、性激素水平变化情况。结果:观察组疗效优于普通针刺组（P<0.05）；药物组精液量优于观察组（P<0.05）；观察组畸形率、a级精子、a+b级精子优于其他3组（P<0.05）；观察组精子活率优于常规温针组、普通针刺组（P<0.05）。观察组精浆果糖、中性α-葡萄糖苷酶优于其他3组（P<0.05）。观察组睾酮优于药物组（P<0.05）；观察组促黄体生成素、促卵泡生成激素优于其他3组（P<0.05）。结论:大艾段温针灸法治疗肾虚肝郁型弱精症疗效肯定，在改善精液常规、精浆生化指标、性激素水平相关参数方面，优于常规温针灸、普通针刺、药物，作用机制可能与调节性激素水平有关。 |
| English Summary: |
| To explore the clinical effect of Da'aiduan warming needle moxibustion on asthenospermia of kidney deficiency and liver depression type.Methods:A total of 140 patients recruited by the research group from January 2018 to December 2019 were randomly divided into an observation group，a drug control group，a conventional warming needling control group and a common needling control group，with 35 cases in each group.The observation group used 4 cm long mugwort segment for warming needling; the drug group used zinc sulfate tablet，vitamin E soft capsule，Wuziyanzong Pill; regular warming needling group used 2.5 cm mugwort segment; common needling group used only conventional needling，without moxibustion.Each group took 4 weeks as a course of treatment.After 2 courses，the changes of symptoms in traditional Chinese medicine，semen conventional indexes，seminal plasma biochemistry and sex hormone level in 4 groups were analyzed.Results:In the aspect of curative effect，the observation group was superior to the ordinary acupuncture group(P<0.05); in the aspect of semen quantity，the drug group was superior to the observation group(P<0.05); in the aspect of deformity rate，class a sperm and class a+a sperm，the observation group was superior to the other three groups(P<0.05); in the aspect of sperm activity rate，the observation group was superior to the conventional warming needling group and the common needling group(P<0.05).Fructose in seminal plasma and neutral α-glucosidase in the observation group were better than those in the other three groups(P<0.05).In terms of testosterone，the observation group was better than the drug group(P<0.05); in terms of luteinizing hormone and follicle stimulating hormone，the observation group was better than the other three groups(P<0.05).Conclusion:The therapeutic effect of Da'aiduan warming needle moxibustion on asthenospermia of kidney deficiency and liver depression type is positive.It is superior to conventional warming needle moxibustion，common acupuncture and medicine in improving semen conventional indexes，seminal plasma biochemistry and related parameters of sexual hormone level.The mechanism of action may be related to regulating sexual hormone level. |
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