After the occurrence of acute myocardial infarction(AMI),a series of complex pathological processes lead to the changes of cardiac structure and cardiac function.Cardiac fibrosis(Myocardial Fibrosis,MF) continues to progress after its formation,leading to a gradual decrease in heart function and a poor prognosis.In recent years,active ingredients derived from Chinese herbal medicine have gradually received widespread attention due to their stable structure and precise efficacy,and may provide valuable candidate compounds for the development of new drugs.The study of the functions and mechanisms of the monomers of traditional Chinese medicine is helpful to find effective treatment drugs for MF after AMI.At present,many experimental studies have found that different kinds of traditional Chinese medicine monomers have different degrees of inhibition on the occurrence and development of MF after AMI,and the mechanisms are different.According to the understanding of the pathogenesis of cardiac fibrosis after myocardial infarction in traditional Chinese medicine,the therapeutic drugs can be selected from qi-invigorating drugs,blood-activating and collateral-activating drugs,warming-yang drugs,etc.The corresponding traditional Chinese medicine monomers are diverse,with different efficacy and mechanism of action.Therefore,the experimental research on the treatment of MF after the treatment of AMI with traditional Chinese medicine is gradually and extensively carried out,and certain results have been obtained.In the future,more relevant researches are still needed for in-depth exploration.