世界中医药
文章摘要
引用本文:郝佳梦1,2,3,4,王丹东1,2,3,4,集川原2,3,4,5,张少兰2,3,4,6,常丽萍2,3,4.射血分数保留型心力衰竭发病机制及治疗进展[J].世界中医药,2021,(11):.  
射血分数保留型心力衰竭发病机制及治疗进展
Progress in Pathogenesis and Treatment of Heart Failure with Preserved Ejection Fraction
投稿时间:2021-04-20  
DOI:10.3969/j.issn.1673-7202.2021.11.007
中文关键词:  心力衰竭  射血分数  心室重构  舒张性心力衰竭  发病机制  治疗  脉络学说
English Keywords:Heart failure  Ejection fraction  Ventricular remodeling  Diastolic heart failure  Pathogenesis  Treatment  Venation theory
基金项目:国家重点研发计划项目(2017YFC1700501)
作者单位
郝佳梦1,2,3,4,王丹东1,2,3,4,集川原2,3,4,5,张少兰2,3,4,6,常丽萍2,3,4 1 河北医科大学研究生院,石家庄,050017
2 河北以岭医院国家中医药管理局中医络病学重点学科,石家庄
050023 3 河北以岭医药研究院国家中医药管理局重点研究室,石家庄050023 4 络病研究与创新中药国家重点实验室,石家庄,050023 5 南京中医药大学研究生院,南京210023 6 河北中医学院研究生院,石家庄050091 
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中文摘要:
      射血分数保留型心力衰竭(HFpEF)约占心力衰竭患者的50%,其高发病率和高死亡率成为目前最具挑战性的临床综合征之一。HFpEF是一种复杂的临床综合征,其生理病理机制复杂,尚无明确定论。大规模临床调查显示以射血分数降低型心力衰竭(HFrEF)常规治疗手段均不能确定降低HFpEF患者发病率和死亡率。现对HFpEF流行病学、病因、诊断、病生理机制及治疗方案进行了简要回顾与总结,以期为该病基础及临床研究提供研究思路。
English Summary:
      Heart failure with preserved ejection fraction(HFpEF) accounts for about 50% of patients with heart failure,and its high morbidity and mortality have become one of the most challenging clinical syndromes.HFpEF is a complex clinical syndrome.The physiological and pathological mechanism is complex,there is no clear conclusion.Large-scale clinical investigation shows that conventional treatment of heart failure with reduced ejection fraction(HFrEF)can not reduce the morbidity and mortality of HFpEF patients.In this paper,the epidemiology,etiology,diagnosis,physiological mechanism and treatment of HFpEF were briefly reviewed and summarized,in order to provide research ideas for the basic and clinical research of the disease.
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