Traditional Chinese medicine(TCM)understands the disease and discusses the law of the occurrence，development and change of the over time.The “Shi fu” disease of TCM is a kind of typical time-related disease，which refers to a kind of disease that occurs in a certain season，ends immediately after the end of the season，and relapses as before in that season in the coming year，which has the characteristics of annual rhythm，recurrence，self-limitation and individuality.The syndrome of lingering pathogen due to deficient vital qi is the cause of the “Shi fu” disease，or due to the incompatibility of the internal and external environment of the human body.It may cause the latent evil spontaneously，or cause the external evil to induce the internal and external evil to induce the recurrent disease.Based on the understanding of the pathogenesis of chronic relapse，the treatment emphasizes measures according to the times.By regulating Zang-fu yin and yang in four seasons，the treatment is rising and falling by four seasons air conditioner，adjusting body cold and heat in four seasons，going out by exorcising evil spirits in four seasons，etc.Meanwhile，we should also pay attention to post-morbid prevention and recovery through rest period conditioning and daily health care in order to cure recurrent illness effectively.