| 引用本文:陈晓丽1，于慧1，孔祥图1，代兴斌1，徐小梦2，倪海雯1.运用癌毒病机理论辨治蕈样肉芽肿[J].世界中医药,2021,(17):. |
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| 运用癌毒病机理论辨治蕈样肉芽肿 |
| Analysis of Syndrome Differentiation and Treatment for Mycosis Fungoidesby Pathogenesis Theory of Cancerous Toxin |
| 投稿时间：2020-11-19 |
| DOI：10.3969/j.issn.1673-7202.2021.17.021 |
| 中文关键词: 癌毒病机理论 蕈样肉芽肿 辨证论治 病因病机 皮肤T细胞淋巴瘤 中西医结合 中医 疗效 |
| English Keywords:Pathogenesis theory of cancerous toxin Mycosis fungoides Syndrome differentiation Etiology and pathogenesis Cutaneous T-cell lymphoma Chinese and Western medicine Traditional Chinese medicine Efficacy |
| 基金项目:国家中医药管理局第四批全国中医优秀人才研修项目（国中医药办人教函〔2017〕24号）；江苏省中医药局科技项目(YB2017014) |
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| 中文摘要: |
| 目的：阐述国医大师周仲瑛教授癌毒病机理论指导下蕈样肉芽肿的病因病机及辨证治疗。方法：基于癌毒病机理论对蕈样肉芽肿的病因病机及辨证治疗进行系统阐释，回顾目前西医治疗的现状及难点，结合具体病案论述中西结合治疗的辨证思路。结果：对疾病早期患者采用以皮肤为靶向的局部治疗，中医辨证多为风热，以祛风清热、凉血解毒为主要治法。随着疾病的进展，采用全身系统治疗为主，病机属虚实夹杂，以益气养阴、凉血解毒为主要治法。结论：蕈样肉芽肿早期诊断困难，确诊主要依靠病理形态学及免疫组织化学。西药综合治疗效果不理想，中医治疗结合癌毒病机理论，分期分阶段紧扣核心病机，可有效控制症状，提高患者生命质量。 |
| English Summary: |
| To narrate the etiology，pathogenesis and syndrome differentiation of the treatment of mycosis fungoides(MF) by ZHOU Zhongying(National TCM Master)'s pathogenesis theory of cancerous toxin.Methods:The pathogenesis and the treatment of MF were systematically expounded based on pathogenesis theory of cancerous toxin.We reviewed the current status and difficulties of Western medicine treatment，and discussed the syndrome differentiation thinking of integrated Chinese and Western medicine combined with specific cases.Results:Patients in early stages of MF were treated with skin-directed therapies.While the TCM syndrome differentiation was based on wind-heat type，and the therapeutic method was focused on wind-expelling，heat-clearing，cooling blood and detoxification.Systemic treatment is mainly used in the advanced stage of the disease.The pathogenesis belonged to a mixture of deficiency and excess，and treated with supplementing qi，nourishing yin，cooling blood and detoxification.Conclusion:Early diagnosis of MF is difficult，and the diagnosis mainly depends on pathomorphology and immune tissue chemotherapy.The comprehensive treatment effect of Western medicine is not satisfactory.TCM treatment combined with the theory of cancer virus pathogenesis，closely focusing on the core pathogenesis in stages，can effectively control symptoms and improve the quality of life of patients. |
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